2-Methyl-2,3,4,4a,5,6-hexahydronaphthalen-1-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Methyl-2,3,4,4a,5,6-hexahydronaphthalen-1-ol
• 英文别名: 2-methyl-2,3,4,4a,5,6-hexahydronaphthalen-1-ol
• 化学式: C₁₁H₁₆O
• 分子量: 164.24
• InChiKey: COMBZXKMRYLNPB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS<br/>[FR] PROCÉDÉ MONOTOPE POUR LA CONVERSION DE CHLORURES D'AROYLE EN ACYL THIO-URÉES
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2014087431A1

  公开（公告）日：2014-06-12

  The present invention disclose an improved one pot process for synthesis of acyl thioureas of formula (I), with yield greater than 80%, from aroyl chlorides of formula (I) wherein, R' is an aryl or a heteroarylene group substituted with one or more groups selected from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino, carboxyl, ester, halogenated hydrocarbon or an aryl or heteroaryl; R" and R"' are selected independently from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino or halogenated hydrocarbon.