(3R)-1,1-diethoxy-3,7-dimethyloctane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3R)-1,1-diethoxy-3,7-dimethyloctane
• 化学式: C₁₄H₃₀O₂
• 分子量: 230.39
• InChiKey: CKAYWEKGUWDSCO-CYBMUJFWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  16
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINING ASYMMETRIC HYDROGENATION AND ISOMERIZATION<br/>[FR] UTILISATION DE MÉLANGES D'ISOMÈRES E/Z EN VUE D'OBTENIR DES PRODUITS SPÉCIFIQUES DE MANIÈRE QUANTITATIVE PAR COMBINAISON D'HYDROGÉNATION ASYMÉTRIQUE ET D'ISOMÉRISATION
  申请人：DSM IP ASSETS BV

  公开号：WO2014096107A1

  公开（公告）日：2014-06-26

  The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves an asymmetric hydrogenation and an isomerization step. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.

  本发明涉及一种从具有可拆手双键的E/Z异构体混合物中制造具有立体中心的化合物的过程。氢化产物在立体中心处具有特定的期望构型。该过程涉及不对称氢化和异构化步骤。该过程非常有利，因为它以高效的方式从起始产物的立体异构体混合物中形成所需的手性产物。
• USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINED ASYMMETRIC HYDROGENATIONS
  申请人：DSM IP ASSETS B.V.

  公开号：US20150321986A1

  公开（公告）日：2015-11-12

  The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves two asymmetric hydrogenation steps. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.

  本发明涉及一种从具有丙型双键的不对称E/Z异构体混合物中制造具有立体异构中心的化合物的过程。氢化产物在立体异构中心处具有特定的所需构型。该过程涉及两个不对称的氢化步骤。该过程非常优越，因为它以高效的方式从起始产品的立体异构体混合物中形成所需的手性产物。
• USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINING ASYMMETRIC HYDROGENATION AND ISOMERIZATION
  申请人：DSM IP ASSETS B.V.

  公开号：US20160185702A1

  公开（公告）日：2016-06-30

  The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves an asymmetric hydrogenation and an isomerization step. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.

  本发明涉及一种从具有原手性双键的不饱和化合物的E/Z异构体混合物中制造具有立体异构中心的化合物的过程。氢化产物在立体异构中心处具有特定的所需构型。该过程涉及不对称氢化和异构化步骤。该过程非常优越，因为它以高效的方式从起始产品的立体异构体混合物中形成所需的手性产物。
• US9458076B2
  申请人：——

  公开号：US9458076B2

  公开（公告）日：2016-10-04
• US9573872B2
  申请人：——

  公开号：US9573872B2

  公开（公告）日：2017-02-21