(3R)-4-[[(3S,4S,6S)-6-[(3S,5S,6S)-6-[(3S,5S,6R)-6-[(3S,5S,6R)-6-[(3S,5S,6R)-6-[(3S,5S,6R)-6-[(3S,4R)-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-[[(2R)-2-methyl-3-oxobutyl]sulfanylmethyl]oxan-3-yl]oxy-2,4,5-trihydroxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methylsulfanyl]-3-methylbutan-2-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3R)-4-[[(3S,4S,6S)-6-[(3S,5S,6S)-6-[(3S,5S,6R)-6-[(3S,5S,6R)-6-[(3S,5S,6R)-6-[(3S,5S,6R)-6-[(3S,4R)-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-2-[[(2R)-2-methyl-3-oxobutyl]sulfanylmethyl]oxan-3-yl]oxy-2,4,5-trihydroxyoxan-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methylsulfanyl]-3-methylbutan-2-one
• 化学式: C₅₁H₈₆O₃₅S₂
• 分子量: 1323.3
• InChiKey: KIEGPOWFAQDEHF-YQZIGDPJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -12.3
• 重原子数：
  88
• 可旋转键数：
  26
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  609
• 氢给体数：
  20
• 氢受体数：
  37

文献信息

• Cyclodextrin-Based Polymers for Therapeutic Delivery
  申请人：Cerulean Pharma Inc.

  公开号：US20140213504A1

  公开（公告）日：2014-07-31

  Described herein are CDP-therapeutic peptide conjugates, therapeutic delivery systems comprising CDP-therapeutic peptide conjugates, compositions comprising CDP-therapeutic peptide conjugates, dosage forms comprising CDP-therapeutic peptide conjugates, and kits comprising CDP-therapeutic peptide conjugates. Also disclosed are methods of using (e.g., to treat a disorder) the CDP-therapeutic peptide conjugates, therapeutic delivery systems comprising CDP-therapeutic peptide conjugates, compositions comprising CDP-therapeutic peptide conjugates, dosage forms comprising CDP-therapeutic peptide conjugates, and kits comprising CDP-therapeutic peptide conjugates.