2-[(4S)-4-amino-5-oxo-5-pyrimidin-2-ylpentyl]guanidine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[(4S)-4-amino-5-oxo-5-pyrimidin-2-ylpentyl]guanidine
• 化学式: C₁₀H₁₆N₆O
• 分子量: 236.27
• InChiKey: VLOUVSLAMOBMQH-ZETCQYMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.5
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  133
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• COMPOSITIONS AND METHODS FOR TREATING COMPLICATIONS ASSOCIATED WITH DIABETES
  申请人：Board of Regents of the University of Nebraska

  公开号：EP2951306A1

  公开（公告）日：2015-12-09
• Compositions and Methods for Treating Complications Associated with Diabetes
  申请人：BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA

  公开号：US20150359862A1

  公开（公告）日：2015-12-17

  Compositions and methods for inhibiting diabetes-related complications are provided.
• [EN] COMPOSITIONS AND METHODS FOR TREATING COMPLICATIONS ASSOCIATED WITH DIABETES<br/>[FR] COMPOSITIONS ET PROCÉDÉS POUR LE TRAITEMENT DE COMPLICATIONS ASSOCIÉES AU DIABÈTE
  申请人：UNIV NEBRASKA

  公开号：WO2014123749A1

  公开（公告）日：2014-08-14

  Compositions and methods for inhibiting diabetes-related complications are provided. Several publications and patent documents are cited throughout the specification in order to describe the state of the art to which this invention pertains. Each of these citations is incorporated herein by reference as though set forth in full. Varying duration insulins, insulin delivery pumps, glucose monitoring 25 devices, food management, and exercise strategies are available to the more than 1.3 million individuals in the USA with Type 1 diabetes (TID), to maintain their blood glucose at near physiological levels.