Dotriacontane-13,15-dione

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Dotriacontane-13,15-dione
• 英文别名: dotriacontane-13,15-dione
• 化学式: C₃₂H₆₂O₂
• 分子量: 478.8
• InChiKey: GZBNFJHBZOAFPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.9
• 重原子数：
  34
• 可旋转键数：
  29
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Stereospecific lipids for locoregional therapy with long-term circulating stimuli-sensitive nanocarrier systems
  申请人：THERMOSOME GmbH

  公开号：US10251838B2

  公开（公告）日：2019-04-09

  The invention relates to stereospecific lipids for the locoregional therapy with long-term circulating stimuli-sensitive nanocarrier systems. A preferred embodiment thereof is a thermosensitive liposome for treating tumors, especially urinary bladder tumors and other localized tumors.

  本发明涉及立体特异性脂质，用于长期循环刺激敏感纳米载体系统的局部治疗。其优选的实施方案是一种用于治疗肿瘤，特别是膀胱肿瘤和其他局部肿瘤的热敏脂质体。
• STEREOSPECIFIC LIPIDS FOR LOCOREGIONAL THERAPY WITH LONG-TERM CIRCULATING STIMULI-SENSITIVE NANOCARRIER SYSTEMS
  申请人：THERMOSOME GmbH

  公开号：US20160136092A1

  公开（公告）日：2016-05-19

  The invention relates to stereospecific lipids for the locoregional therapy with long-term circulating stimuli-sensitive nanocarrier systems. A preferred embodiment thereof is a thermosensitive liposome for treating tumors, especially urinary bladder tumors and other localized tumors.
• [EN] NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING TRACKING AND METHODS OF MAKING AND USING THEREOF<br/>[FR] NANOPARTICULES POUR LE SUIVI DE L'IMAGERIE PAR RÉSONANCE MAGNÉTIQUE ET PROCÉDÉS DE FABRICATION ET D'UTILISATION ASSOCIÉS
  申请人：UNIV JOHNS HOPKINS

  公开号：WO2014124006A1

  公开（公告）日：2014-08-14

  Surface conjugated diamagnetic Chemical Exchange Saturation Transfer (diaCEST) agent carriers and methods of making and using are described herein. The particles are safe alternatives to conventional paramagnetic or superparamagnetic metal-based MRI contrast agents that are often toxic and therefore not biocompatible. The carriers described herein can provide simultaneous monitoring of multiple particle types labeled with 'multicolor' diaCEST contrast agents. In some embodiments, the carriers are micro- and/or nanoparticles. In other embodiments, the carriers are liposomes. In some embodiments, the particles and/or liposomes are mucus penetrating. In other embodiments, the particles and/or liposomes are not mucus penetrating.