(3S,4S,6S)-6-[[(2S,4S,5S)-3-acetamido-2-ethyl-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxymethyl]-4,5-dihydroxy-3-methoxyoxane-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3S,4S,6S)-6-[[(2S,4S,5S)-3-acetamido-2-ethyl-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxymethyl]-4,5-dihydroxy-3-methoxyoxane-2-carboxylic acid
• 化学式: C₁₈H₃₁NO₁₁
• 分子量: 437.4
• InChiKey: PFRBBBCLYDQXMW-AEXUKQEPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  30
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  184
• 氢给体数：
  6
• 氢受体数：
  11

文献信息

• INHIBITOR FOR CORNEAL EPITHELIAL CELL DEATH, INHIBITOR CHARACTERIZED BY COMBINING HYALURONIC ACID AND FLAVIN ADENINE DINUCLEOTIDE
  申请人：SANTEN PHARMACEUTICAL CO., LTD.

  公开号：US20140228425A1

  公开（公告）日：2014-08-14

  A combination of hyaluronic acid or a salt thereof and flavin adenine dinucleotide or a salt thereof can be an inhibitor for corneal epithelial cell death induced by ultraviolet irradiation and/or dryness because it significantly inhibits the decline of the number of living cells in corneal epithelial cells induced by ultraviolet irradiation or dryness.