5-Amino-2-(aminomethyl)-6-propan-2-yloxane-3,4-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-Amino-2-(aminomethyl)-6-propan-2-yloxane-3,4-diol
• 英文别名: 5-amino-2-(aminomethyl)-6-propan-2-yloxane-3,4-diol
• 化学式: C₉H₂₀N₂O₃
• 分子量: 204.27
• InChiKey: MZXWZCXVXDRYSB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  102
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• Methods for chemical synthesis of biologically active compounds using supramolecular protective groups and novel compounds obtainable Thereby
  申请人：Herrmann Andreas

  公开号：US20140243280A1

  公开（公告）日：2014-08-28

  The invention relates to drug development and synthetic chemistry, in particular to the manufacture of biologically active compounds based on naturally occurring molecules. It also relates to novel biologically active compounds, for example aminoglycoside antibiotics, in a substantially pure regioisomeric form.

  这项发明涉及药物开发和合成化学，特别是基于天然分子制造生物活性化合物。它还涉及新型生物活性化合物，例如氨基糖苷类抗生素，以较纯的位置异构形式存在。
• Methods for Chemical Synthesis of Biologically Active Compounds Using Supramolecular Protective Groups and Novel Compounds Obtainable Thereby
  申请人：Rijksuniversiteit Groningen

  公开号：US20180105546A1

  公开（公告）日：2018-04-19

  The invention relates to drug development and synthetic chemistry, in particular to the manufacture of biologically active compounds based on naturally occurring molecules. It also relates to novel biologically active compounds, for example aminoglycoside antibiotics, in a substantially pure regioisomeric form. More particularly, the present invention relates to methods for the chemo- or regioselective derivatization of a target compound with multiple reactive groups, some of which may be derivatezed, and other which will not be derivatized.