[(2S,3S,5R)-4-hydroxy-5-[(2R,3S,5S)-4-hydroxy-5-methoxy-6-(propan-2-ylcarbamoyl)-3-sulfooxyoxan-2-yl]oxy-2-methoxy-6-(sulfooxymethyl)oxan-3-yl]sulfamic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(2S,3S,5R)-4-hydroxy-5-[(2R,3S,5S)-4-hydroxy-5-methoxy-6-(propan-2-ylcarbamoyl)-3-sulfooxyoxan-2-yl]oxy-2-methoxy-6-(sulfooxymethyl)oxan-3-yl]sulfamic acid
• 化学式: C₁₇H₃₂N₂O₁₉S₃
• 分子量: 664.6
• InChiKey: OGGPXBBXADBLMB-QXPZFHCTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.9
• 重原子数：
  41
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  334
• 氢给体数：
  7
• 氢受体数：
  20

文献信息

• Method for functionalizing a porous membrane covering of an optical sensor to facilitate coupling of an antithrom-bogenic agent
  申请人：MEDTRONIC MINIMED, INC.

  公开号：US10352941B2

  公开（公告）日：2019-07-16

  Methods of covalently attaching heparin to a membrane comprising plasma treating the membrane to produce an amino-functionalized membrane; and reacting the amino-functionalized membrane with heparin under conditions in which heparin becomes covalently attached to the amino-functionalized membrane, wherein said heparin is indirectly attached via a spacer to said amino-functionalized membrane and/or said heparin is attached from a single site in said heparin to a single site on said amino-functionalized membrane or to said spacer. Also disclosed are analyte sensors.

  将肝素共价连接到膜上的方法，包括等离子体处理膜以产生氨基官能化膜；以及使氨基官能化膜与肝素反应，反应条件为肝素共价连接到氨基官能化膜上，其中所述肝素通过间隔物间接连接到所述氨基官能化膜上，和/或所述肝素从所述肝素中的单个位点连接到所述氨基官能化膜上的单个位点或所述间隔物上。还公开了分析物传感器。
• METHOD FOR FUNCTIONALIZING A POROUS MEMBRANE COVERING OF AN OPTICAL SENSOR TO FACILITATE COUPLING OF AN ANTITHROM-BOGENIC AGENT
  申请人：MEDTRONIC MINIMED, INC.

  公开号：US20140242710A1

  公开（公告）日：2014-08-28

  Methods of covalently attaching heparin to a membrane comprising plasma treating the membrane to produce an amino-functionalized membrane; and reacting the amino-functionalized membrane with heparin under conditions in which heparin becomes covalently attached to the amino-functionalized membrane, wherein said heparin is indirectly attached via a spacer to said amino-functionalized membrane and/or said heparin is attached from a single site in said heparin to a single site on said amino-functionalized membrane or to said spacer. Also disclosed are analyte sensors.