(1S,8R,10R,11R)-5-methyl-10-[(2-methylpropan-2-yl)oxy]-3-pentyl-9-oxa-4,5,6-triazatricyclo[6.3.0.02,6]undec-2-ene-1,11-diol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1S,8R,10R,11R)-5-methyl-10-[(2-methylpropan-2-yl)oxy]-3-pentyl-9-oxa-4,5,6-triazatricyclo[6.3.0.02,6]undec-2-ene-1,11-diol
• 化学式: C₁₇H₃₁N₃O₄
• 分子量: 341.4
• InChiKey: ZYNLHABGDNJTLD-JWDQPFGJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  77.4
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• [EN] SUBSTITUTED SUGAR DERIVED 1, 2, 3-TRIAZOLE COMPOUNDS AND THEIR DIMERS AND A PROCESS FOR THE PREPARATION THEREOF<br/>[FR] COMPOSÉS 1, 2, 3-TRIAZOLES DÉRIVÉS DE SUCRES SUBSTITUÉS ET LEURS DIMÈRES AINSI QU'UN PROCÉDÉ POUR LEUR PRÉPARATION
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2014132273A1

  公开（公告）日：2014-09-04

  The present invention discloses tricyclic five membered sugar derived 1,2,3-triazoles compounds of formula I and their dimers and a process for the preparation thereof. Particularly, the present invention relates to tricyclic five membered sugar derived 1,2,3-triazoles compounds of formula I which are useful for screening of various kinases and other related targets. [Insert formula I here] wherein R is selected from hydrogen, (un)substituted or substituted alkyl, (un)substituted or substituted aryl, (un)substituted or substituted cycloalkyls, (un)substituted or substituted heteroaryls.