β-cyclodextrin

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: β-cyclodextrin
• 英文别名: β-cyclodextrine；cyclodextrin；β-CD；I(2)-cyclodextrin；(1S,5R,6S,10R,11S,15R,16S,20R,21S,25R,26S,30R,31S,35R,36R,37R,38R,39R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R)-5,10,15,20,25,30,35-heptakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane-36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecol
• 化学式: C₄₂H₇₀O₃₅
• 分子量: 1135.0
• InChiKey: WHGYBXFWUBPSRW-VOXAOYDDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -15
• 重原子数：
  77
• 可旋转键数：
  7
• 环数：
  21.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  554
• 氢给体数：
  21
• 氢受体数：
  35

文献信息

• COMPOSITIONS COMPRISING AN RNA POLYMERASE INHIBITOR AND CYCLODEXTRIN FOR TREATING VIRAL INFECTIONS
  申请人：Gilead Sciences, Inc.

  公开号：US20190083525A1

  公开（公告）日：2019-03-21

  The present disclosure provides a composition comprising Compound 1, or a pharmaceutically acceptable salt thereof, cyclodextrin, and, optionally, pH adjusting agents.

  本公开提供了一种组合物，其包括化合物1或其药学上可接受的盐、环糊精以及可选的pH调节剂。
• Compositions comprising an RNA polymerase inhibitor and cyclodextrin for treating viral infections
  申请人：Gilead Sciences, Inc.

  公开号：US10675296B2

  公开（公告）日：2020-06-09

  The present disclosure provides a composition comprising Compound 1, or a pharmaceutically acceptable salt thereof, cyclodextrin, and, optionally, pH adjusting agents.

  本公开提供了一种组合物，其中包含化合物 1 或其药学上可接受的盐、环糊精以及可选的 pH 调整剂。
• Method of producing purified stilbene compounds
  申请人：MORINAGA & CO., LTD.

  公开号：US10730815B2

  公开（公告）日：2020-08-04

  The present invention is directed to provide a precipitate obtained by adding γ-cyclodextrin to a liquid containing a stilbene compound. The precipitate according to the present invention is used as the precipitate obtained by adding γ-cyclodextrin to the liquid containing a stilbene compound.

  本发明旨在提供一种通过向含有二苯乙烯化合物的液体中添加γ-环糊精而获得的沉淀。根据本发明的沉淀用作向含有二苯乙烯化合物的液体中加入γ-环糊精得到的沉淀。
• Injectable phenol formulations and methods of their use
  申请人：SAOL INTERNATIONAL DEVELOPMENT LTD.

  公开号：US11083694B2

  公开（公告）日：2021-08-10

  Phenol formulations including phenol and an encapsulation agent, such as a cyclodextrin or derivatives thereof, and uses of such formulations.

  包括苯酚和封装剂（如环糊精或其衍生物）的苯酚制剂及其用途。
• Injectable phenol formulations and methods of manufacture
  申请人：SAOL INTERNATIONAL DEVELOPMENT LTD.

  公开号：US11083695B2

  公开（公告）日：2021-08-10

  Phenol formulations including phenol and an encapsulation agent, such as a cyclodextrin or derivatives thereof, and uses of such formulations.

  包括苯酚和封装剂（如环糊精或其衍生物）的苯酚制剂及其用途。