3-[(5-Amino-2-methylpentyl)amino]propanal

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-[(5-Amino-2-methylpentyl)amino]propanal
• 英文别名: 3-[(5-amino-2-methylpentyl)amino]propanal
• 化学式: C₉H₂₀N₂O
• 分子量: 172.27
• InChiKey: ISSNXFOHWOUZGC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  12
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  55.1
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] MODIFIED POLY(BETA-AMINO ESTER)S FOR DRUG DELIVERY<br/>[FR] POLY(BÊTA-AMINO-ESTERS) MODIFIÉS POUR L'ADMINISTRATION D'UN MÉDICAMENT
  申请人：INST QUÍMIC DE SARRI CETS FUNDACIÓ PRIVADA

  公开号：WO2014136100A1

  公开（公告）日：2014-09-12

  Disclosed are polymers that are poly(beta-amino ester)s (PBAEs) modified with at least one oligopeptide. The polymers may be used in any field where polymers have been found useful including in medical fields, particularly in drug delivery. The polymers are particularly useful in delivering a polynucleotide such as DNA, RNA and siRNA, a small molecule or a protein. Also disclosed are compositions comprising said polymers and an active agent, methods of encapsulating an agent in a matrix of said polymers, and said polymers and compositions for use in medicine.
• [EN] POLY(BETA-AMINO ESTER)S WITH ADDITIVES FOR DRUG DELIVERY<br/>[FR] POLY(BÊTA-AMINO ESTERS) AVEC ADDITIFS POUR L'ADMINISTRATION D'UN MÉDICAMENT
  申请人：SAGETIS BIOTECH S L

  公开号：WO2016116887A1

  公开（公告）日：2016-07-28

  Disclosed are nanoparticles comprising an end-modified poly(β-amino ester) and an additive that is a sugar or sugar derivative, such as a sugar, a sugar alcohol or chitosan. The nanoparticles may be used in any field where polymers have been found useful, including in medical fields, particularly in drug delivery. The polymers are useful in delivering a polynucleotide such as DNA, RNA or siRNA, a small molecule or a protein. Also disclosed are compositions comprising said nanoparticles and an active agent, methods for preparing said nanoparticles, said nanoparticles and compositions for use in medicine, and in vitro methods using said nanoparticles and compositions.