(3aR,6aR)-6-ethyl-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3aR,6aR)-6-ethyl-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-ol
• 化学式: C₉H₁₆O₄
• 分子量: 188.22
• InChiKey: CYQOLMJDVCSUOR-MIDKJMSJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Process for the Preparation of 4-Amino-1-((1S,4R,5S)-2-Fluoro-4,5-Dihydroxy-3-Hydroxymethyl-Cyclopent-2-Enyl)-1H-Pyrimidin-2-One
  申请人：Rexahn Pharmaceuticals, Inc.

  公开号：US20150376142A1

  公开（公告）日：2015-12-31

  Processes for the preparation of 4-amino-1((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one (13, RX-3117) and its intermediates are described.

  本文描述了制备4-氨基-1-((1S,4R,5S)-2-氟-4,5-二羟基-3-羟甲基环戊-2-烯基)-1H-嘧啶-2-酮（13，RX-3117）及其中间体的工艺过程。
• US20140275537A1
  申请人：——

  公开号：US20140275537A1

  公开（公告）日：2014-09-18
• COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS
  申请人：Astrocyte Pharmaceuticals, Inc.

  公开号：US20180021363A1

  公开（公告）日：2018-01-25

  The present invention relates to compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries.
• FLUOROCYCLOPENTENYLCYTOSINE METHODS OF USE
  申请人：Rexahn Pharmaceuticals, Inc.

  公开号：US20180021338A1

  公开（公告）日：2018-01-25

  The disclosed subject matter provides methods using and kits comprising a compound of formula (I) or a hydrate, a solvate, or a pharmaceutically acceptable salt thereof. The disclosed subject matter further provides a method of treating one or more symptoms of cancer comprising administering to a subject in need thereof a compound of formula (I) and a process for preparing such.
• US9150520B2
  申请人：——

  公开号：US9150520B2

  公开（公告）日：2015-10-06