1,3-Bis(5-methoxy-2-nitrophenyl)propan-2-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 1,3-Bis(5-methoxy-2-nitrophenyl)propan-2-one
• 英文别名: 1,3-bis(5-methoxy-2-nitrophenyl)propan-2-one
• 化学式: C17H16N2O7
• 分子量: 360.3
• InChiKey: YJFXUQFZCBXBSR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  127
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• PHOTOCLEAVABLE DEOXYNUCLEOTIDES WITH HIGH-RESOLUTION CONTROL OF DEPROTECTION KINETICS
  申请人：Ibis Biosciences, Inc.

  公开号：EP2970365A1

  公开（公告）日：2016-01-20
• [EN] PHOTOCLEAVABLE DEOXYNUCLEOTIDES WITH HIGH-RESOLUTION CONTROL OF DEPROTECTION KINETICS<br/>[FR] DÉSOXYNUCLÉOTIDES PHOTOCLIVABLES AVEC CONTRÔLE À HAUTE RÉSOLUTION DES CINÉTIQUES DE DÉPROTECTION
  申请人：IBIS BIOSCIENCES INC

  公开号：WO2014150845A1

  公开（公告）日：2014-09-25

  Provided herein are new classes of photocleavable deoxynucleotides that allow for more precise control over deprotection kinetics compared to previously described compounds. The compounds further feature more favorable solubility properties. The nucleotides find use in methods such as next-generation sequencing. A series of molecules are provided with defined organic substituents that allow fine tuning of the deprotection kinetics when irradiated with an appropriate light source.