1,2-bis-heptyloxy-ethane | 32822-37-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,2-bis-heptyloxy-ethane
• 英文别名: 1,2-Bis-heptyloxy-aethan；1-(2-Heptoxyethoxy)heptane
• CAS: 32822-37-0
• 化学式: C₁₆H₃₄O₂
• 分子量: 258.445
• InChiKey: WPBRSJSZQSTTPX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  18
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  乙二醇 在 sodium 作用下， 生成 庚氧基乙醇 、 1,2-bis-heptyloxy-ethane
  参考文献：
  名称：

  91.抗结核化合物。第六部分 p-（ω-烷氧基烷氧基）-N-芳基苯甲m及其类似物

  摘要：

  DOI：

  10.1039/jr9500000459

文献信息

• METHOD FOR PURIFYING TETRAKIS(FLUOROARYL) BORATE/MAGNESIUM HALIDE, TETRAKIS(FLUOROARYL) BORATE/ETHER COMPLEX AND PROCESS FOR PREPARING THE SAME, AND PROCESS FOR PREPARING TETRAKIS(FLUOROARYL) BORATE DERIVATIVE
  申请人：Nippon Shokubai Co., Ltd.

  公开号：EP0913400A1

  公开（公告）日：1999-05-06

  A method for purifying Ar4 BMgX which comprises treating a tetrakis(fluoroaryl) borate/magnesium halide (Ar4BMgX) with (1) an alkaline (earth) metal salt of carboxylic acid, (2) an acid, (3) an acid and then an alkaline (earth) metal hydroxide, or (4) an acid and then an alkaline (earth) metal salt of carboxylic acid; and a process for preparing a tetrakis(fluoroaryl) borate derivative (Ar4BZ) which comprises reacting the treated Ar4BMgX with a compound capable of generating monovalent cationic species. The above purification method permits separation and removal of impurities contained in Ar4 BMgX in an efficient and simple manner. The invention also provides a tetrakis(fluoroaryl) borate/ether complex, a process for preparing the same, and a process for preparing a tetrakis(fluoroaryl) borate derivative (Ar4BZ) by using the ether complex and the compound capable of generating monovalent cationic species as starting compounds. The ether complex can be easily purified to a high purity and hence is suitable as an intermediate for the preparation of various tetrakis(fluoroaryl) borate derivatives.

  一种提纯 Ar4 BMgX 的方法，包括用(1)羧酸的碱(土)金属盐、(2)酸、(3)酸然后碱(土)金属氢氧化物或(4)酸然后羧酸的碱(土)金属盐处理四(氟芳基)硼酸盐/卤化镁(Ar4BMgX)；以及制备四（氟芳基）硼酸酯衍生物（Ar4BZ）的工艺，包括将处理过的 Ar4BMgX 与能够生成一价阳离子物种的化合物反应。上述纯化方法可以高效、简单地分离和去除 Ar4 BMgX 中所含的杂质。本发明还提供了一种四(氟芳基)硼酸酯/醚络合物、制备四(氟芳基)硼酸酯/醚络合物的工艺，以及以醚络合物和能够生成一价阳离子种类的化合物为起始化合物制备四(氟芳基)硼酸酯衍生物(Ar4BZ)的工艺。醚络合物很容易提纯到高纯度，因此适合用作制备各种四（氟芳基）硼酸酯衍生物的中间体。
• Tetrakis(fluoroaryl) borate/ether complexes and process for preparing the same
  申请人：Nippon Shokubai Co., Ltd.

  公开号：EP1400524A1

  公开（公告）日：2004-03-24

  The invention provides a tetrakis(fluoroaryl) borate/ether complex, and the process for preparing the same, The ether complex can be easily purified to a high purity and hence is suitable as an intermediate for the preparation of various tetrakis(fluoroaryl)borate derivatives.

  本发明提供了一种四(氟芳基)硼酸酯/醚络合物及其制备方法，该醚络合物很容易提纯到高纯度，因此适合作为制备各种四(氟芳基)硼酸酯衍生物的中间体。
• Process for preparing tetrakis (fluoroaryl) borate derivatives
  申请人：Nippon Shokubai Co., Ltd.

  公开号：EP1400525A1

  公开（公告）日：2004-03-24

  The invention provides a tetrakis(fluoroaryl) borate/ether complex, a process for preparing the same, and a process for preparing a tetrakis(fluoroaryl)borate derivative (Ar4BZ) by using the ether complex and the compound capable of generating monovalent cationic species as starting compounds. The ether complex can be easily purified to a high purity and hence is suitable as an intermediate for the preparation of various tetrakis(fluoroaryl)borate derivatives.

  本发明提供了一种四(氟芳基)硼酸酯/醚络合物、制备该络合物的工艺，以及使用该醚络合物和能够生成一价阳离子物种的化合物作为起始化合物制备四(氟芳基)硼酸酯衍生物(Ar4BZ)的工艺。醚络合物很容易提纯到高纯度，因此适合用作制备各种四（氟芳基）硼酸酯衍生物的中间体。
• Purifying process of tetrakis (fluoroaryl) borate.magnesium halide, tetrakis (fluoroaryl) borate.ether complex and producing process of the same, and producing process of tetrakis (fluoroaryl) borate derivative
  申请人：NIPPON SHOKUBAI CO., LTD.

  公开号：US20010014739A1

  公开（公告）日：2001-08-16

  Tetrakis(fluoroaryl)borate•magnesium halide (Ar 4 BMgX) expressed by General Formula (1): 1 where each of R 1 -R 10 represents a hydrogen atom, a fluorine atom, a hydrocarbon group, or an alkoxy group, provided that at least one of R 1 -R 5 represents a fluorine atom and at least one of R 6 -R 10 represents a fluorine atom, X represents a chlorine atom, a bromine atom, or an iodide atom, and n represents 2 or 3, is treated with alkali metal salts of carboxylic acid and/or alkali earth metal salts of carboxylic acid. Then, a tetrakis(fluoroaryl)borate derivative (Ar 4 BZ) is produced by reacting treated Ar 4 BMgX with a compound generating monovalent cation seeds (for example, N,N-dimethylaniline•hydrochloride). Consequently, it has become possible to provide a purifying process of separating/removing impurities from Ar 4 BMgX readily and efficiently, and a process of producing inexpensive Ar 4 BX efficiently.

  四（氟芳基）硼酸镁卤化物（Ar 4 BMgX），通式（1）表示： 1 其中每个 R 1 -R 10 代表氢原子、氟原子、烃基或烷氧基，条件是 R 1 -R 5 中的至少一个代表氟原子，且 R 6 -R 10 代表氟原子，X 代表氯原子、溴原子或碘原子，n 代表 2 或 3、 用羧酸的碱金属盐和/或羧酸的碱土金属盐处理。然后，四(氟芳基)硼酸酯衍生物（Ar 4 BZ）。 4 BMgX 与产生一价阳离子种子的化合物（例如 N,N-二甲基苯胺盐酸盐）反应，就可以制得四(氟芳基)硼酸酯衍生物（Ar 4 BZ）。因此，可以提供一种纯化工艺来分离/去除 Ar 4 BMgX 中分离/去除杂质的纯化工艺，以及生产廉价 Ar 4 BX 的高效生产工艺。
• US6215025B1
  申请人：——

  公开号：US6215025B1

  公开（公告）日：2001-04-10