[(2S,4S,5S)-5-[(2R,4S,5S)-3-azido-4,5-dimethyl-6-(phenylmethoxymethyl)oxan-2-yl]oxy-2-[(3S,4R,6S)-5-azido-6-methoxy-4-methyl-2-(phenylmethoxymethyl)oxan-3-yl]oxy-4,6-dimethyloxan-3-yl] benzoate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(2S,4S,5S)-5-[(2R,4S,5S)-3-azido-4,5-dimethyl-6-(phenylmethoxymethyl)oxan-2-yl]oxy-2-[(3S,4R,6S)-5-azido-6-methoxy-4-methyl-2-(phenylmethoxymethyl)oxan-3-yl]oxy-4,6-dimethyloxan-3-yl] benzoate
• 化学式: C44H56N6O10
• 分子量: 828.9
• InChiKey: GYUAKZWDAHYGHY-OZXXYCMCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  60
• 可旋转键数：
  18
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  129
• 氢给体数：
  0
• 氢受体数：
  14

文献信息

• Production Of L-Iduronate Containing Polysaccharides
  申请人：Hansen Steen Uldall

  公开号：US20100317846A1

  公开（公告）日：2010-12-16

  A process for the production of polysaccharide (20) from disaccharide (10) and saccharide (21), wherein R 1 to R 10 are each independently the same or different protecting groups; R is an optionally substituted aryl group or an optionally substituted saturated or unsaturated alkyl group; X is selected from the group consisting of hydrogen, alkyl and amino; Y is selected from the group consisting of a protecting group and one or more saccharide residues; and n is a positive integer; and further wherein said process comprises removal of the R 7 protecting group and reaction of the deprotected C4-oxygen atom of compound (21) with the C1-carbon atom of the 1-ido moiety of compound (10).

  从二糖（10）和糖（21）中生产多糖（20）的工艺，其中R1至R10分别是相同或不同的保护基；R是可选的取代芳基或可选的饱和或不饱和烷基；X选自氢，烷基和氨基等组；Y选自保护基和一个或多个糖基残基；n是正整数；并且进一步包括去除R7保护基和使化合物（21）的去保护的C4氧原子与化合物（10）的1-碘基团的C1碳原子反应的步骤。