3-Methyl-oxacycloundecan-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 3-Methyl-oxacycloundecan-2-one
• 英文别名: 3-methyl-oxacycloundecan-2-one
• 化学式: C₁₁H₂₀O₂
• 分子量: 184.27
• InChiKey: JXDRPRMIGHNJPO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• PRODUCTION OF INGENOL, INGENOL ESTERS AND/OR TIGLIAN-3-ONE DERIVATIVES BY EUPHORBIACEAE PLANT CELL SUSPENSION CULTURES
  申请人：Phyton Holdings, LLC

  公开号：EP3270686A1

  公开（公告）日：2018-01-24
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：EP3356356A1

  公开（公告）日：2018-08-08
• HIGH INTENSITY SWEETENERS
  申请人：Senomyx, Inc.

  公开号：EP3368542A2

  公开（公告）日：2018-09-05
• [EN] PRODUCTION OF INGENOL, INGENOL ESTERS AND/OR TIGLIAN-3-ONE DERIVATIVES BY EUPHORBIACEAE PLANT CELL SUSPENSION CULTURES<br/>[FR] PRODUCTION D'INGÉNOL, D'ESTERS D'INGÉNOL ET/OU DE DÉRIVÉS DE TIGLIAN-3-ONE PAR DES CULTURES CELLULAIRES DE PLANTES D'EUPHORBIACÉES EN SUSPENSION
  申请人：PHYTON BIOTECH GMBH

  公开号：WO2016150860A1

  公开（公告）日：2016-09-29

  The present invention relates to a method of producing Ingenol, Ingenol esters and/or Tiglian- 3-one derivatives, the method comprising the steps of: (a) culturing plant cells obtained from a plant selected from the family Euphorbiaceae in a nutrient medium in a suspension cell culture, wherein the cells produce Ingenol, one or more Ingenol esters and/or one or more Tiglian-3-one derivatives; and (b) recovering the Ingenol, the one or more Ingenol esters and/or the one or more Tiglian-3-one derivatives produced in (a). The present invention further relates to a plant suspension cell culture, wherein the cells are obtained from a plant selected from the family Euphorbiaceae, and wherein the plant cells produce Ingenol and/or one or more Ingenol ester and/or one or more Tiglian-3-one derivatives. The present invention further relates to a plant cell biomass comprising plant cells obtained from the suspension cell culture of the invention, and comprising Ingenol and/or one or more Ingenol esters and/or one or more Tiglian-3-one derivatives. Also, the present invention relates to cryopreserved cells of the plant suspension cell culture of the invention as well as to a method of producing Ingenol, Ingenol esters and/or Tiglian-3-one derivatives based on these cryopreserved cells.
• [EN] HIGH INTENSITY SWEETENERS<br/>[FR] ÉDULCORANTS À INTENSITÉ ÉLEVÉE
  申请人：SENOMYX INC

  公开号：WO2017075257A2

  公开（公告）日：2017-05-04

  Disclosed herein are compounds having structural Formula (I), or salts thereof. These compounds are useful as sweet tasting agents and/or sweetness enhancers. Also disclosed are compositions comprising the present compounds and methods of increasing the sweet taste of ingestible compositions. Furthermore, methods for preparing the compounds are also disclosed.