3-Ethyl-6-(hydroxymethyl)oxane-2,4,5-triol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Ethyl-6-(hydroxymethyl)oxane-2,4,5-triol
• 英文别名: 3-ethyl-6-(hydroxymethyl)oxane-2,4,5-triol
• 化学式: C₈H₁₆O₅
• 分子量: 192.21
• InChiKey: HEEDIDYNMLFVRG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  90.2
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• [EN] TUCARESOL DERIVATIVES AND USES THEREOF<br/>[FR] DÉRIVÉS DE TUCARESOL ET LEURS UTILISATIONS
  申请人：BEYONDSPRING PHARMACEUTICALS INC

  公开号：WO2021096811A1

  公开（公告）日：2021-05-20

  Disclosed herein are tucaresol derivative compound and composition containing the same. Also disclosed herein are methods of enhancing immune response in a subject by administering the tucaresol derivative compound or by co-administering the tucaresol derivative compound and one or more additional agents. Also disclosed herein are use of the tucaresol derivative compound and composition containing the same in the manufacture of a medicament for treating cancer or enhancing immune response in a subject.

  本文披露了一种tucaresol衍生物化合物和含有该化合物的组合物。本文还披露了通过给予tucaresol衍生物化合物或同时给予tucaresol衍生物化合物和一个或多个额外药剂来增强受试者的免疫反应的方法。本文还披露了将tucaresol衍生物化合物和含有该化合物的组合物用于制造用于治疗癌症或增强受试者免疫反应的药物的用途。
• US9120814B2
  申请人：——

  公开号：US9120814B2

  公开（公告）日：2015-09-01
• [EN] AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME<br/>[FR] AGENTS CIBLANT LES AMYLOÏDES ET MÉTHODES DE LEUR UTILISATION
  申请人：[en]THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：WO2022266210A1

  公开（公告）日：2022-12-22

  Described herein, inter alia, are molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins, and methods for treating diseases associated with an amyloid or amyloid like proteins.