2-[(3S,3aR,5R,7aS)-3a-acetyl-3-hydroxy-7a-methyl-2,3,4,5,6,7-hexahydro-1H-inden-5-yl]prop-2-enoic acid | 117869-89-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[(3S,3aR,5R,7aS)-3a-acetyl-3-hydroxy-7a-methyl-2,3,4,5,6,7-hexahydro-1H-inden-5-yl]prop-2-enoic acid
• CAS: 117869-89-3
• 化学式: C₁₅H₂₂O₄
• 分子量: 266.33
• InChiKey: QHMVDJGMBDTIEY-DHMWGJHJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-[(3S,3aR,5R,7aS)-3a-acetyl-3-hydroxy-7a-methyl-2,3,4,5,6,7-hexahydro-1H-inden-5-yl]prop-2-enoic acid 、 重氮甲烷 以95%的产率得到
  参考文献：
  名称：

  CECCHERELLI, PAOLO;CURINI, MASSIMO;MARCOTULLIO, MARIA CARLA;MENGHINI, ALE+, J. NATUR. PROD., 51,(1988) N 5, C. 1006-1009

  摘要：

  DOI：

文献信息

• SYNTHESIS AND APPLICATION OF CHIRAL SUBSTITUTED POLYVINYLPYRROLIDINONES
  申请人：Kansas State University Research Foundation

  公开号：US20200306737A1

  公开（公告）日：2020-10-01

  Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.

  手性聚乙烯吡咯烷酮（CSPVP），CSPVP与金属纳米团簇催化剂等核心物种形成的络合物，以及利用这种络合物进行对映选择氧化反应的方法被揭示。CSPVP络合物可用于不对称二醇氧化、烯烃对映选择氧化以及碳-碳键形成反应等。CSPVP还可以与蛋白质、DNA和RNA等生物分子形成络合物，并用作siRNA或dsRNA传递的纳米载体。
• CECCHERELLI, PAOLO;CURINI, MASSIMO;MARCOTULLIO, MARIA CARLA;MENGHINI, ALE+, J. NATUR. PROD., 51,(1988) N 5, C. 1006-1009
  作者：CECCHERELLI, PAOLO、CURINI, MASSIMO、MARCOTULLIO, MARIA CARLA、MENGHINI, ALE+

  DOI：——

  日期：——
• [EN] SYNTHESIS AND APPLICATION OF CHIRAL SUBSTITUTED POLYVINYLPYRROLIDINONES<br/>[FR] SYNTHÈSE ET APPLICATION DE POLYVINYLEPYRROLIDINONES SUBSTITUÉES CHIRALES
  申请人：UNIV KANSAS STATE

  公开号：WO2017172763A1

  公开（公告）日：2017-10-05

  Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.