Spiro[2.5]oct-7-en-2-ol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Spiro[2.5]oct-7-en-2-ol
• 英文别名: spiro[2.5]oct-7-en-2-ol
• 化学式: C₈H₁₂O
• 分子量: 124.18
• InChiKey: CSEFXKSTHQZQNH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• TRICYCLIC SPIRO COMPOUND
  申请人：ONO PHARMACEUTICAL CO., LTD.

  公开号：US20180002308A1

  公开（公告）日：2018-01-04

  A medicinal agent for the prevention and/or treatment of diseases caused by EP 4 receptor activation. A compound having antagonistic activity against the EP 4 receptor is contained as an active ingredient in the medicinal agent. The compound represented by the following general formula (I) as defined in the specification, a salt, an N-oxide, or a solvate thereof, or a prodrug of these is useful as a medicinal component having antagonistic activity against the EP 4 receptor for the prevention and/or treatment of diseases caused by EP 4 receptor activation.