2,3-Dimethyl-5,6-bis(hydroxymethyl)-1,4-benzochinon | 52643-60-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,3-Dimethyl-5,6-bis(hydroxymethyl)-1,4-benzochinon
• 英文别名: 2,3-Bis(hydroxymethyl)-5,6-dimethylcyclohexa-2,5-diene-1,4-dione
• CAS: 52643-60-4
• 化学式: C₁₀H₁₂O₄
• 分子量: 196.203
• InChiKey: MACWITOHKSKXGM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,3-Dimethyl-5,6-bis(hydroxymethyl)-1,4-benzochinon 、 异氰酸乙酯 生成 Ethyl-carbamic acid 2-ethylcarbamoyloxymethyl-4,5-dimethyl-3,6-dioxo-cyclohexa-1,4-dienylmethyl ester
  参考文献：
  名称：

  潜在的生物还原烷基化剂。3.苯醌的乙酰氧基甲基和相应的氨基甲酸乙酯衍生物的合成和抗肿瘤活性。

  摘要：

  DOI：

  10.1021/jm00251a026
• 作为产物：
  描述：

  2-嘧啶胺,4-(3-溴-2-噻嗯基)-6-甲基- 生成 2,3-Dimethyl-5,6-bis(hydroxymethyl)-1,4-benzochinon
  参考文献：
  名称：

  潜在的生物还原烷基化剂。3.苯醌的乙酰氧基甲基和相应的氨基甲酸乙酯衍生物的合成和抗肿瘤活性。

  摘要：

  DOI：

  10.1021/jm00251a026

文献信息

• Water-soluble compositions of bioactive lipophilic compounds
  申请人：National Research Council of Canada

  公开号：EP1985308A2

  公开（公告）日：2008-10-29

  A solubilizing agent of the formula          X-OOC-(CH2)n-COO-Y wherein X is a member selected from campesterol, sitosterol, ergosterol and stigmasterol; Y is a member selected from polyalcohol, polyether, polyanion, polycation, polyphosphoric acid, polyamine, polysaccharide, polyhydroxy compound and polylysine, and derivatives thereof; and n is an integer selected from 0 to 18. The solubilizing agent may be included in a water-soluble composition comprising a bioactive lipophilic compound and the solubilizing agent.

  式中的增溶剂 X-OOC-(CH2)n-COO-Y 其中 X 选自坎培甾醇、西固醇、麦角甾醇和豆甾醇； Y 是选自多元醇、聚醚、聚阴离子、聚阳离子、聚磷酸、聚胺、多糖、多羟基化合物和聚赖氨酸及其衍生物的成员；以及 n 是选自 0 至 18 的整数。 增溶剂可包含在由生物活性亲脂化合物和增溶剂组成的水溶性组合物中。
• WATER-SOLUBLE COMPOSITIONS OF BIOACTIVE LIPOPHILIC COMPOUNDS
  申请人：NATIONAL RESEARCH COUNCIL OF CANADA

  公开号：EP1159006B1

  公开（公告）日：2008-09-10
• DERMAL COMPOSITIONS CONTAINING COENZYME Q AS THE ACTIVE INGREDIENT
  申请人：FUJII Kenji

  公开号：US20110070213A1

  公开（公告）日：2011-03-24

  The present invention provides a composition for dermal application which comprises, as an active ingredient, an oxidized coenzyme Q represented by the formula (1): in which n represents an integer of 1 to 12, and/or a reduced coenzyme Q represented by the formula (2): in which n represents an integer of 1 to 12, the total content of the oxidized coenzyme Q and reduced coenzyme Q being 0.01 to 99% by weight relative to the whole amount of the composition. The present invention also provides a therapeutic composition for skin diseases, a cosmetic composition, a skin health care composition and a bath salt composition, each comprising the above composition for dermal application. The present invention is further provides a method for the treatment of skin diseases which comprises applying, to a patient suffering from a skin disease, the above-mentioned therapeutic composition for skin diseases, or a method for the treatment of skin diseases which comprises applying, to a patient suffering from a skin disease, the above therapeutic agent for skin diseases other than the oxidized coenzyme Q represented by the formula (1) and other than the reduced coenzyme Q represented by the formula (2) in parallel with a therapeutic composition for skin diseases.
• PIG FEED, AND METHOD FOR FEEDING SAME
  申请人：Ohara Takaaki

  公开号：US20130136724A1

  公开（公告）日：2013-05-30

  An object of the present invention is to provide a method for improving a farrowing rate of sows or improving growth and productivity of postnatal piglets, and a feed used in the method. The present invention relates to a method for improving a farrowing rate of a sow or improving growth and productivity of postnatal piglets, the method comprising administering coenzyme Q to a swine.
• US7645816B2
  申请人：——

  公开号：US7645816B2

  公开（公告）日：2010-01-12