3'-iso-Propyl-3-methylbutyrophenone

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3'-iso-Propyl-3-methylbutyrophenone
• 英文别名: 3-methyl-1-(3-propan-2-ylphenyl)butan-1-one
• 化学式: C₁₄H₂₀O
• 分子量: 204.31
• InChiKey: PAHXVBIQLABHDN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Monocyclic, Thieno, Pyrido, and Pyrrolo Pyrimidine Compounds and Methods of Use and Manufacture of the Same
  申请人：Duquesne University of the Holy Spirit

  公开号：US20170050978A1

  公开（公告）日：2017-02-23

  The present invention provides a compound of Formula I: wherein R is H, a methyl group, an ethyl group, a n-propyl group, an iso-propyl group, or a n-butyl group; and R 1 is H, a 4′-methyl group, a 4′-OH, a 4′-OMe group, a 2′,3′-C 2 H 4 group, a; 3′,4′-C 2 H 4 group, a 3′,4′-diF, a 3′,4′,5′-triF, or a 4′-OCF 3 ; and optionally including a salt or a hydrate of said compound, and further provides a pharmaceutical composition comprising the compound of Formula I and one or more acceptable pharmaceutical carriers. A method of treating a patient having cancer comprising administering a therapeutically effective amount of a compound of Formula I, or a pharmaceutical composition comprising a compound of Formula I and one or more acceptable pharmaceutical carriers to the patient is disclosed.
• US9994586B2
  申请人：——

  公开号：US9994586B2

  公开（公告）日：2018-06-12