Adipiodone, dimeglumine salt | 3521-84-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Adipiodone, dimeglumine salt
• 英文别名: 3-[[6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid;6-(methylamino)hexane-1,2,3,4,5-pentol
• CAS: 3521-84-4
• 化学式: C34H48I6N4O16
• 分子量: 1530.2
• InChiKey: DGIAUNUPXILTJW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.13
• 重原子数：
  60
• 可旋转键数：
  21
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  359
• 氢给体数：
  16
• 氢受体数：
  18

制备方法与用途

类别：有毒物品

毒性分级：中毒

急性毒性：

• 静脉注射大鼠 LD50：5000 毫克/公斤
• 静脉注射小鼠 LD50：3195 毫克/公斤

可燃性危险特性：可燃；燃烧时产生有毒氮氧化物和碘化物烟雾

储运特性：通风、低温、干燥

灭火剂：干粉、泡沫、沙土、二氧化碳、雾状水

文献信息

• EP2576778B1
  申请人：——

  公开号：EP2576778B1

  公开（公告）日：2017-08-09
• TRANSGENIC REPORTER SYSTEM THAT REVEALS EXPRESSION PROFILES AND REGULATION MECHANISMS OF ALTERNATIVE SPLICING IN MAMMALIAN ORGANISMS
  申请人：Hagiwara Masatoshi

  公开号：US20130137099A1

  公开（公告）日：2013-05-30

  An object of the present invention is to develop a new alternative splicing reporter system and to provide a method for detecting alternative splicing patterns in a mammalian multicellular organism more precisely, a method for identifying efficiently substances and gene regions that affect alternative splicing in a mammalian multicellular organism, and the like by utilizing the alternative splicing reporter system. Specifically, the present invention relates to a method for detecting alternative splicing in a mammalian multicellular organism, and a method for identifying substances and gene regions that affect alternative splicing in a mammalian multicellular organism, which use a DNA construct in which at least two different reporter genes are inserted into a specific gene that undergoes alternative splicing, or a combination of DNA constructs (a combination of at least two different DNA constructs) in which DNA construct a reporter gene is inserted into a specific gene that undergoes alternative splicing.
• US9273364B2
  申请人：——

  公开号：US9273364B2

  公开（公告）日：2016-03-01