Taraktophyllin | 110115-55-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Taraktophyllin
• 英文别名: (1R,4S)-4-hydroxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclopent-2-ene-1-carbonitrile
• CAS: 110115-55-4
• 化学式: C₁₂H₁₇NO₇
• 分子量: 287.27
• InChiKey: JRCWYCAEAZEYNW-UKXAOYPBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.3
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  143
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• Compositions and methods for treating infectious disease
  申请人：Sichtnik Laszlo

  公开号：US10183964B2

  公开（公告）日：2019-01-22

  Provided are cyanogenic compositions for treating diseases, such as infectious diseases.

  本发明提供了用于治疗疾病（如传染性疾病）的生氰组合物。
• COMPOSITIONS AND METHODS FOR TREATING INFECTIOUS DISEASE
  申请人：Sichtnik, Laszlo

  公开号：EP2968377B1

  公开（公告）日：2020-07-22
• Extracts of Cranberry and Methods of Using Thereof
  申请人：Alberte Randall S.

  公开号：US20100028469A1

  公开（公告）日：2010-02-04

  The present disclosure relates in part to extracts of cranberry ( Vaccinium macrocarpon ) comprising an enriched amount of certain compounds having anti-infective activity, e.g. antibacterial and/or antifungal activity, e.g. activity against C. albicans . Another aspect of the disclosure relates to combined cranberry and cinnamon extracts. In certain embodiments, these combined extracts have been optimized to control urinary tract infections caused by E. coli, S. aureus and C. albicans . Certain embodiments of the extract are enriched in bioactive compounds that have been shown to inhibit C. albicans adhesion and/or biofilm formation and its growth in vitro. In another aspect of the disclosure, the extracts are enriched in bioactives derived from cranberry and cinnamon that have been shown to inhibit the attachment and the growth of common urinary tract pathogens like E. coli, S. aureus and C. albicans.
• [EN] COMPOSITIONS AND METHODS FOR TREATING INFECTIOUS DISEASE<br/>[FR] COMPOSITIONS ET MÉTHODES POUR TRAITER UNE MALADIE INFECTIEUSE
  申请人：SICHTNIK LASZLO

  公开号：WO2014165057A1

  公开（公告）日：2014-10-09

  Provided are cyanogenic compositions for treating infectious diseases.