Erythromycin, monohydrate | 67733-56-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Erythromycin, monohydrate
• 英文别名: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione;hydrate
• CAS: 67733-56-6
• 化学式: C37H69NO14
• 分子量: 751.9
• InChiKey: XGYMKYQKIUWFJD-YZPBMOCRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.96
• 重原子数：
  52
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  195
• 氢给体数：
  6
• 氢受体数：
  15

文献信息

• SELECTIVE OXIDATION OF C-H BONDS OF MODIFIED SUBSTRATES BY P450 MONOOXYGENASE
  申请人：Li Shengying

  公开号：US20120190635A1

  公开（公告）日：2012-07-26

  The present invention provides regio- and stereoselective oxidation of unactivated C—H bonds using an engineered mutant cytochrome P450 monooxygenase and an engineered substrate.

  本发明提供了使用经过改造的突变型细胞色素P450单氧酶和经过改造的底物对非活化的C-H键进行区域和立体选择性氧化的方法。
• PRESSURE-SENSITIVE ADHESIVE FOR SKIN SURFACE AND/OR TRANSDERMAL SUBSTANCE DELIVERY
  申请人：Hauser Ray L.

  公开号：US20090317451A1

  公开（公告）日：2009-12-24

  A pressure-sensitive adhesive composition is described having a reservoir of medication or other substance and capable of intimate contact with a target area of skin, rapid conveyance of the medication onto and/or into the target area, and ready removal from the area of skin using water. Polyvinylpyrrolidone and glycerol mixtures have been found to dissolve a large number of medications while producing a self-tackifying, pressure-sensitive adhesive composition.
• US4751220A
  申请人：——

  公开号：US4751220A

  公开（公告）日：1988-06-14
• [EN] SELECTIVE OXIDATION OF C-H BONDS OF MODIFIED SUBSTRATES BY P450 MONOOXYGENASE<br/>[FR] OXYDATION SÉLECTIVE DE LIAISONS C-H DE SUBSTRATS MODIFIÉS PAR UNE MONO-OXYGÉNASE À P450
  申请人：UNIV MICHIGAN

  公开号：WO2011038313A2

  公开（公告）日：2011-03-31

  The present invention provides regio- and stereoselective oxidation of unactivated C-H bonds using an engineered mutant cytochrome P450 monooxygenase and an engineered substrate.