[(2S,3S,4R,5R)-4-(2-甲基丙酰氧基)-2,5-二(2-甲基丙酰氧基甲基)-2-[(2R,3R,4S,5R,6R)-3,4,5-三(2-甲基丙酰氧基)-6-(2-甲基丙酰氧基甲基)四氢吡喃-2-基]氧基四氢呋喃-3-基]2-甲基丙酸酯 | 102787-19-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: [(2S,3S,4R,5R)-4-(2-甲基丙酰氧基)-2,5-二(2-甲基丙酰氧基甲基)-2-[(2R,3R,4S,5R,6R)-3,4,5-三(2-甲基丙酰氧基)-6-(2-甲基丙酰氧基甲基)四氢吡喃-2-基]氧基四氢呋喃-3-基]2-甲基丙酸酯
• 英文名称: Sucrose octaisobutyrate
• 英文别名: [(2R,3R,4S,5R,6R)-6-[(2S,3S,4R,5R)-3,4-bis(2-methylpropanoyloxy)-2,5-bis(2-methylpropanoyloxymethyl)oxolan-2-yl]oxy-3,4,5-tris(2-methylpropanoyloxy)oxan-2-yl]methyl 2-methylpropanoate
• CAS: 102787-19-9
• 化学式: C₄₄H₇₀O₁₉
• 分子量: 903.0
• InChiKey: QSOGLNCCKWUXRN-CIGKAFDASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  63
• 可旋转键数：
  29
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  238
• 氢给体数：
  0
• 氢受体数：
  19

文献信息

• [EN] SOLUTION COMPRISING FLUORESCENT DYE AS FIDUCIAL MARKER<br/>[FR] SOLUTION COMPRENANT UN MARQUEUR FLUORESCENT EN TANT QUE MARQUEUR DE RÉFÉRENCE
  申请人：UNIV DANMARKS TEKNISKE

  公开号：WO2019243422A1

  公开（公告）日：2019-12-26

  The present disclosure relates to a solution comprising a water insoluble carbohydrate and a fluorescent dye, such as a near infrared (NIR) contrast agent, wherein the solution sets under aqueous conditions, such as in vivo, to form e.g. a gel, a glass, a semi-solid, a solid, a crystal or any mixtures thereof. The disclosure further relates to preparation of such solution and use of such solution for in vivo imaging and/or guidance of surgery or interventional therapeutic procedures.

  本公开涉及一种溶液，包括一种水不溶性碳水化合物和一种荧光染料，例如一种近红外（NIR）对比剂，其中该溶液在水性条件下，例如在体内，形成例如凝胶、玻璃、半固体、固体、晶体或其任何混合物。该公开进一步涉及制备这种溶液和使用这种溶液进行体内成像和/或手术或介入治疗程序的指导。
• [EN] DISSACHARIDE FORMULATIONS FOR CONTROLLED DRUG RELEASE<br/>[FR] FORMULATIONS DE DISACCHARIDES POUR LA LIBÉRATION CONTRÔLÉE DE MÉDICAMENTS
  申请人：UNIV DENMARK TECH DTU

  公开号：WO2020249801A1

  公开（公告）日：2020-12-17

  The present invention relates to a composition comprising non-water soluble dissacharides and oil, a solvent and at least one pharmaceutical ingredient, wherein the composition contains at least two compounds selected from saccharides and lipid oils such as lactose octabenzoate Methyl hepta-O-isobutyryl-α,β-lactoside, α,β-Lactose octa para-iodobenzoate, 3-iodobenzyl hepta-O-isobutyryl-α,β-lactoside, lactose octapropionate, lactose octaisobutyrate, sucrose octabenzoate, glycerol trihexanoate, Glycerol trioctanoate, Glycerol tridecanoate, Lipiodol, ethyl myristate, ethyl palmitate, ethyl oleoate and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 2,000 centipoise (cP) after administration.

  本发明涉及一种组合物，包括不溶于水的双糖和油、溶剂和至少一种药物成分，其中该组合物含有至少两种从糖类和脂肪油中选择的化合物，例如乳糖八苯甲酸酯、甲基庚烯基七-O-异丁酰-α，β-乳糖苷、α，β-乳糖八对碘苯甲酸酯、3-碘苯甲基七-O-异丁酰-α，β-乳糖苷、乳糖八丙酸酯、乳糖八异丁酸酯、蔗糖八苯甲酸酯、三己酸甘油酯、三辛酸甘油酯、三癸酸甘油酯、利碘油、肉豆蔻酸乙酯、棕榈酸乙酯、油酸乙酯，其中该组合物在注入人体或动物体内之前为液体，并在注入后黏度增加超过2,000厘泊（cP）。
• [EN] 1,4,7,10-TETRAAZABICYCLO[8.2.2]TETRADECAN-2-ONE, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR THE PREPARATION OF TETRAAZAMACROCYCLES<br/>[FR] 1,4,7,10-TETRAAZABICYCLO 8.2.2 TETRADECAN-2-ONE, LEUR PROCEDE DE PREPARATION ET LEUR UTILISATION DANS LA PREPARATION DE TETRAAZAMACROCYCLES
  申请人：BRACCO S.P.A.

  公开号：WO1999005145A1

  公开（公告）日：1999-02-04

  (EN) The present invention relates to the novel compound, 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one of formula (I), its preparation and the use thereof for the preparation of tetraazamacrocycles.(FR) La présente invention concerne le nouveau composé 1,4,7,10-tétraazabicyclo 8.2.2 tetradecan-2-one représenté par la formule (I), sa préparation et son utilisation dans la préparation de tétraazamacrocycles.

  本发明涉及一种新的化合物，即式(I)中的1,4,7,10-四氮杂双环[8.2.2]四十二烷-2-酮，以及其制备和用于制备四氮杂大环化合物的用途。
• An emulsion concentrate for soft drinks
  申请人：QUEST INTERNATIONAL B.V.

  公开号：EP0925727A2

  公开（公告）日：1999-06-30

  The invention provides a process for the preparation of an emulsion concentrate for soft drinks comprising emulsifying in an aqueous extract of crushed defatted seeds from edible fruit, a flavour mixture comprising an essential oil of the peel of least one citrus fruit and/or an organoleptically neutral oil. Citrus fruit is preferred. Preferably the oil/solids ratio is from 1.5 : 1 to 5 : 1. Preferably the citrus fruit seeds comprise orange (Citrus aurantium) seeds and/or grapefruit (Citrus paradisi) seeds. The emulsion concentrate may further comprise estergum, damar resin and/or sucrose diacetyl hexaisobuturate. Preferably the aqueous phase of the emulsion concentrate is adjusted to a pH between 2.5 and 6, more preferably by the addition of citric acid. The invention further provides an emulsion concentrate so prepared as well as a soft drink obtainable by diluting the emulsion concentrate.

  本发明提供了一种用于制备软饮料的浓缩乳液的工艺，该工艺包括在可食用水果脱脂种子的粉碎水提取物中乳化由至少一种柑橘类水果果皮精油和/或有机中性油组成的风味混合物。首选柑橘类水果。油/固体的比例最好为 1.5 : 1 至 5 : 1。柑橘类水果的种子最好是橙子和/或葡萄柚的种子。乳液浓缩物还可包括酯胶、达玛树脂和/或蔗糖二乙酰六异丁酸酯。最好将乳液浓缩物的水相调节到 2.5 至 6 之间的 pH 值，更优选加入柠檬酸。 本发明进一步提供了一种如此制备的浓缩乳液以及一种通过稀释浓缩乳液而获得的软饮料。
• Compositions for improving the health and appearance of skin
  申请人：Algenist Holdings, Inc.

  公开号：US10231907B2

  公开（公告）日：2019-03-19

  Provided herein are microalgal skin care compositions and methods of improving the health and appearance of skin. Also provided are methods of using polysaccharides for applications such as topical personal care products, cosmetics, and wrinkle reduction compositions. The invention also provides novel decolorized microalgal compositions useful for improving the health and appearance of skin. The invention also includes insoluble polysaccharide particles for application to human skin.

  本文提供了微藻护肤组合物以及改善皮肤健康和外观的方法。还提供了将多糖用于局部个人护理产品、化妆品和除皱组合物等应用的方法。本发明还提供了用于改善皮肤健康和外观的新型脱色微藻组合物。本发明还包括用于人体皮肤的不溶性多糖颗粒。