Salicylic acid glucoside | 10366-91-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Salicylic acid glucoside
• 英文别名: 2-[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoic acid
• CAS: 10366-91-3
• 化学式: C₁₃H₁₆O₈
• 分子量: 300.26
• InChiKey: TZPBMNKOLMSJPF-TWEVDUBQSA-N

物化性质

• 沸点：
  591.6±50.0 °C(Predicted)
• 密度：
  1.588
• 溶解度：
  DMSO（少许）、甲醇（少许）、水（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  -1.5
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  137
• 氢给体数：
  5
• 氢受体数：
  8

文献信息

• ISOLATION AND CHARACTERISATION OF THE CSB3-1 MUTANT OF ARABIDOPSIS THALIANA AND USE THEREOF AS A REGULATOR OF RESISTANCE IN PLANTS TO DISEASES CAUSED BY BIOTROPHIC PATHOGENS
  申请人：Consejo Superior de Investigaciones Cientificas

  公开号：EP1908838A2

  公开（公告）日：2008-04-09

  The invention relates to the technical field of plant biotechnology and, more specifically, to the identification and characterization of the csb3-1 mutant of Arabidopsis thaliana, as well as to the use thereof in the regulation of resistance to diseases caused by biotrophic pathogens and to the applications of same in the generation of plants that are resistant to said type of pathogens.

  本发明涉及植物生物技术领域，更具体地说，涉及拟南芥 csb3-1 突变体的鉴定和特征描述，以及将其用于调节对由生物营养型病原体引起的疾病的抗性，并将其应用于培育对上述类型病原体具有抗性的植物。
• Methods for treating tauopathy
  申请人：The J. David Gladstone Institutes

  公开号：US10004753B2

  公开（公告）日：2018-06-26

  The present disclosure provides methods of reducing the level of acetylated Tau in a neuron or a glial cell in an individual, the methods involving administering to the individual a prodrug that is converted in the individual to salicylate. The present disclosure provides methods of treating a tauopathy in an individual, the methods involving administering to the individual a prodrug that is converted in the individual to salicylate.

  本公开提供了降低个体神经元或神经胶质细胞中乙酰化Tau水平的方法，这些方法涉及向个体施用在个体体内转化为水杨酸盐的原药。本公开提供了治疗个体Tau病的方法，这些方法涉及对个体施用在个体体内转化为水杨酸盐的原药。
• Polishing agent, stock solution for polishing agent, and polishing method
  申请人：Hitachi Chemical Company, Ltd.

  公开号：US10946494B2

  公开（公告）日：2021-03-16

  A polishing agent for polishing a resin comprises abrasive grains, a water-soluble polymer having an ether bond, an organic solvent and water, wherein the abrasive grains have a positive charge in the polishing agent and an average particle diameter of the abrasive grains is larger than 20 nm.

  一种用于抛光树脂的抛光剂由磨粒、具有醚键的水溶性聚合物、有机溶剂和水组成，其中磨粒在抛光剂中带有正电荷，磨粒的平均颗粒直径大于 20 纳米。
• A METHOD OF PRODUCING A LOW MOLECULAR WEIGHT ORGANIC COMPOUND IN A CELL
  申请人：Poalis A/S

  公开号：EP1649029A1

  公开（公告）日：2006-04-26
• METHODS FOR TREATING TAUOPATHY
  申请人：The J. David Gladstone Institutes

  公开号：EP3244914A1

  公开（公告）日：2017-11-22