蒽醌-2-磺酸钠单水合物 | 153277-35-1

• 物质功能分类: 化学试剂 - 有机试剂 - 芳香酮
• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 中文名称: 蒽醌-2-磺酸钠单水合物
• 中文别名: 蒽醌-2-磺酸钠一水合物
• 英文名称: sodium 9,10-dioxo-9,10-dihydroanthracene-2-sulfonate hydrate
• 英文别名: sodium anthraquinone-2-sulfonate hydrate；Silbersalz；2-anthraquinonesulfonic acid sodium salt monohydrate；anthraquinone-2-sulfonic acid sodium salt monohydrate；sodium;9,10-dioxoanthracene-2-sulfonate;hydrate
• CAS: 153277-35-1
• 化学式: C₁₄H₇O₅S*H₂O*Na
• 分子量: 328.278
• InChiKey: KHILLYASAGTPOI-UHFFFAOYSA-M

物化性质

• 熔点：
  >300 °C(lit.)
• 溶解度：
  H2O：可溶0.1g/10 mL，澄清，无色至淡黄色
• 稳定性/保质期：
  遵照规定使用和储存，则不会分解。

计算性质

• 辛醇/水分配系数(LogP)：
  -2.45
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  101
• 氢给体数：
  1
• 氢受体数：
  6

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• 储存条件：
  存于阴凉干燥处

制备方法与用途

蒽醌-2-磺酸钠单水合物是一种化学物质，具有刺激眼睛、呼吸道和皮肤的作用。它主要用于生物碱的分析试剂，并广泛应用于染料合成及有机合成等行业。

反应信息

• 作为反应物：
  描述：

  2,6-dichloro-isonicotinic acid, silver (I)-compound 、 蒽醌-2-磺酸钠单水合物 生成 2,6-二氯吡啶
  参考文献：
  名称：

  Sell; Dootson, Journal of the Chemical Society, 1900, vol. 77, p. 237

  摘要：

  DOI：
• 作为产物：
  描述：

  cyanomethylnitrolic acid 、 silver nitrate 生成 蒽醌-2-磺酸钠单水合物
  参考文献：
  名称：

  Steinkopf, Chemische Berichte, 1909, vol. 42, p. 620

  摘要：

  DOI：

文献信息

• Assessing Chronic Exposure to Fumonisin Mycotoxins: The Use of Hair as a Suitable Noninvasive Matrix
  作者：V. Sewram、J. J. Nair、T. W. Nieuwoudt、W. C. A. Gelderblom、W. F. O. Marasas、G. S. Shephard

  DOI：10.1093/jat/25.6.450

  日期：2001.9.1

  This study describes for the first time the accumulation of measurable levels of fumonisin mycotoxins in the hair of nonhuman primates (vervet monkeys, Cercopithecus aethiops) and rats exposed to contaminated feed. Hair was subjected to reflux with methanol, and the resulting extract was cleaned up on strong anion exchange (SAX) and C18 solid-phase sorbents. Fumonisins FB1, FB2, and FB3 as well as their hydrolysis products commonly known as aminopolyols, AP1 and AP2, were detected in monkey hair using high-performance liquid chromatography coupled to electrospray ionization mass spectrometry (HPLC-ESI-MS). Despite matrix interferences, the two-stage mass spectrometric process (MS-MS) yielded product ion mass spectra, which served as diagnostic indicators thus providing unequivocal identification of FB1, FB2, and FB3 as well as AP1 and AP2. In vervet monkeys, the levels of exposure related well to the levels of toxin detected in hair, and levels as high as 5.98 mg FB1, 33.77 mg FB1, and 65.93 mg FB1/kg of hair were found in monkeys receiving control, low-dose, and high-dose contaminated diets, respectively. Hair was also analyzed from rats given either single gavage doses of 1 and 10 mg FB1/kg body weight or contaminated feed (50 mg FB1/kg), resulting in an exposure of approximately 4.25 mg FB1/kg body weight/day based on the measured daily feed intake. Analysis of rat hair over a four-week period indicated that mean levels up to 34.50 mg/kg and 42.20 mg/kg were detectable by the fourth week in the rats treated by gavage (10 mg FB1/kg body weight) and those receiving contaminated feed, respectively. This relationship indicates that hair can provide an easily applicable non-invasive matrix for assessing chronic exposure to fumonisin mycotoxins.

  这项研究首次描述了非人类灵长类动物（小猕猴，Cercopithecus aethiops）和暴露于污染饲料的老鼠的毛发中可测量的呕吐霉素（fumonisin）毒素的积累情况。毛发经过甲醇回流处理，提取物在强阴离子交换（SAX）和C18固相吸附剂上进行清理。使用高效液相色谱-电喷雾电离质谱联用技术（HPLC-ESI-MS）检测到了小猕猴毛发中的呕吐霉素FB1、FB2和FB3及其水解产物，通常被称为氨基多醇（aminopolyols），AP1和AP2。尽管存在基质干扰，两阶段质谱过程（MS-MS）产生的产物离子质谱作为诊断指标，从而无可置疑地识别了FB1、FB2和FB3以及AP1和AP2。在小猕猴中，曝光水平与毛发中检测到的毒素水平相关，接受对照组、低剂量和高剂量污染饮食的猴子毛发中分别发现高达5.98 mg FB1、33.77 mg FB1和65.93 mg FB1/kg的含量。对老鼠的毛发分析显示，给予1和10 mg FB1/kg体重的单次灌胃剂量或污染饲料（50 mg FB1/kg）后，基于测得的每日饲料摄入量，暴露量大约为4.25 mg FB1/kg体重/天。在为期四周的实验中，灌胃处理（10 mg FB1/kg体重）和接受污染饲料的老鼠在第四周时的平均毛发中可检测到的水平分别高达34.50 mg/kg和42.20 mg/kg。这一关系表明，毛发可以作为评估对呕吐霉素毒素慢性暴露的一个易于应用的非侵入性基质。
• Oxygen scavenging compositions
  申请人：——

  公开号：US20040099840A1

  公开（公告）日：2004-05-27

  Epoxy anthraquinonesulfonamide compounds are disclosed having the Formula (I) wherein X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 and X 8 are each independently selected from H, OH, NH 2 , C 1 -C 40 alkyl, C 1 -C 40 alkoxy, C 1 C 40 alkanoyl, C 1 -C 40 alkanol, C 1 -C 40 alkylether, C 1 -C 40 alkylthio, C 1 -C 40 alkylamino, C 1 -C 40 alkanolether, C 1 -C 40 alkylaminoether, C 1 -C 40 alkylsulfonyl, C 1 -C 40 alkyl sulfonanmido, epoxy sulfonamido substituents, and sulfonate substituents, with the proviso that at least one of X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 and X 8 is an epoxy sulfonamido substituent, and salts thereof. The compounds and reaction products thereof may be used in oxygen scavenging compositions. 1

  本发明公开了具有式(I)的环氧蒽醌磺酰胺化合物，其中X1、X2、X3、X4、X5、X6、X7和X8各自独立地选自H、OH、NH2、C1-C40烷基、C1-C40烷氧基、C1-C40酰基、C1-C40醇基、C1-C40烷醚基、C1-C40烷硫基、C1-C40烷基氨基、C1-C40烷醚氨基、C1-C40烷基磺酰基、C1-C40烷基磺酰胺取代基和磺酸盐取代基，但至少其中一个为环氧磺酰胺取代基，以及它们的盐。这些化合物及其反应产物可用于氧清除组合物中。
• COMPOSITIONS, METHODS, AND ARTICLES RELATING TO IN-SITU CROSSLINKING OF POLYAMIDES DURING ADDITIVE MANUFACTURING
  申请人：Xerox Corporation

  公开号：EP4006080A1

  公开（公告）日：2022-06-01

  Particles may be produced that comprise an unsaturated polyamide and an initiator. Said particles may be used in additive manufacturing methods that comprise: depositing the particles optionally in combination with other thermoplastic polymer particles upon a surface; and once deposited, heating at least a portion of the particles to promote consolidation thereof and crosslinking of the unsaturated polyamide, thereby forming a consolidated body comprising a crosslinked polyamide.

  可生产由不饱和聚酰胺和引发剂组成的颗粒。所述颗粒可用于增材制造方法，该方法包括：将颗粒（可选择与其他热塑性聚合物颗粒一起）沉积在表面上；沉积后，加热至少一部分颗粒，以促进其固结和不饱和聚酰胺的交联，从而形成由交联聚酰胺组成的固结体。
• Nef, Justus Liebigs Annalen der Chemie, 1891, vol. 266, p. 105
  作者：Nef

  DOI：——

  日期：——
• Baeyer, Justus Liebigs Annalen der Chemie, 1876, vol. 183, p. 31
  作者：Baeyer

  DOI：——

  日期：——