Calcium 2-methoxyethanolate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Calcium 2-methoxyethanolate
• 英文别名: calcium;2-methoxyethanolate
• 化学式: C6H14CaO4
• 分子量: 190.25
• InChiKey: OFPISIUOJVZBMS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.39
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  64.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (1,1,3-Trioxo-1,3-dihydro-1λ⁶-benzo[d]isothiazol-2-yl)-acetic acid 2-methoxy-ethyl ester 、 Calcium 2-methoxyethanolate 生成 Bis(2-methoxyethyl) 2-(N-carboxymethylsulfamoyl)benzoate
  参考文献：
  名称：

  SVOBODA, J.;PALECEK, J.;DEDEK, V., COLLECT. CZECHOSL. CHEM. COMMUN., 1986, 51, N 5, 1133-1139

  摘要：

  DOI：

文献信息

• PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT
  申请人：Chugai Seiyaku Kabushiki Kaisha

  公开号：US20190225604A1

  公开（公告）日：2019-07-25

  The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

  本发明提供一种化合物，其具有通过取代基连接的式（I）所示的基本结构，其中吲哚环和吡唑吡啶结构通过取代基相连，以及包含该化合物、盐或该化合物的盐的溶剂的预防剂或治疗剂，用作非胰岛素依赖型糖尿病（2型糖尿病）或肥胖症的活性成分。
• PROCESS FOR CONTINUOUS PRODUCTION OF ORGANIC CARBONATES OR ORGANIC CARBAMATES AND SOLID CATALYSTS THEREFORE
  申请人：Ryu J. Yong

  公开号：US20090203933A1

  公开（公告）日：2009-08-13

  Processes for the alcoholysis, inclusive of transesterification and/or disproportionation, of reactants are disclosed. The alcoholysis process may include feeding reactants and a trace amount of soluble organometallic compound to a reactor comprising a solid alcoholysis catalyst, wherein the soluble organometallic compound and the solid alcoholysis catalyst each independently comprise a Group II to Group VI element, which may be the same element in various embodiments. As an example, diphenyl carbonate may be continuously produced by performing transesterification over a solid catalyst followed by disproportionation, where a trace amount of soluble organometallic compound is fed to the transesterification reactor. Also disclosed is a process for reactivating a spent solid alcoholysis catalyst, such as a catalyst useful for transesterifications and/or disproportionations, the process including removing polymeric materials deposited on the catalyst and re-depositing catalytically active metals on the solid catalyst.

  公开了有关醇解反应的过程，包括酯交换和/或不均化。醇解过程可能包括将反应物和微量可溶性有机金属化合物送入包含固体醇解催化剂的反应器中，其中可溶性有机金属化合物和固体醇解催化剂各自独立地包含第二至第六族元素，这些元素在不同实施例中可能是相同的元素。例如，可以通过在固体催化剂上进行酯交换然后进行不均化来连续生产二苯碳酸酯，其中微量可溶性有机金属化合物被送入酯交换反应器。还公开了一种用于再生用于酯交换和/或不均化的废弃固体醇解催化剂的过程，包括去除沉积在催化剂上的聚合物材料并在固体催化剂上重新沉积具有催化活性的金属。
• Resurrection Of Antibiotics That MRSA Resists By Silver-Doped Bioactive Glass-Ceramic Particles
  申请人：Board of Trustees of Michigan State University

  公开号：US20200330510A1

  公开（公告）日：2020-10-22

  A method of treating a bacterial infection including bacteria that have become resistant to an antibiotic in a subject in need thereof is provided. The method includes administering to the subject a safe and therapeutically effective amount of the antibiotic and a reviving agent selected from the group consisting of glass-ceramic particles, silver ions, and combinations thereof. The reviving agent restores antibiotic activity to the antibiotic against the bacteria.

  提供了一种治疗细菌感染的方法，包括对抗生素产生抗药性的细菌，适用于需要该方法的患者。该方法包括向患者施用安全和治疗有效量的抗生素和从以下组合中选择的复活剂：玻璃陶瓷粒子、银离子或两者的组合。复活剂可以使抗生素对抗细菌恢复活性。
• Borate-glass biomaterials
  申请人：THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/McGILL UNIVERSITY

  公开号：US10507263B2

  公开（公告）日：2019-12-17

  Borate-glass biomaterials comprising: aNa2O. bCaO. cP2O5. dB2O3 wherein a is from about 1-40 wt %, b is from about 10-40 wt %, c is from about 1-40 wt %, and d is from about 35-80 wt %; and wherein the biomaterial has a surface area per mass of more than about 5 m2/g. Methods of making and uses of these biomaterials.

  硼酸玻璃生物材料包括：aNa2O，bCaO，cP2O5，dB2O3，其中a约为1-40重量％，b约为10-40重量％，c约为1-40重量％，d约为35-80重量％；并且生物材料的每重量表面积大约超过5 m2 / g。制备这些生物材料的方法和用途。
• Alkali metal-containing, organometallic products
  申请人：The National Hellenic Research Foundation

  公开号：US03932545A1

  公开（公告）日：1976-01-13

  An alkali metal-containing, organometallic product, which is hydrocarbon-soluble, is prepared by reacting an organo-alkali metal reactant in which the alkali metal atom is bonded to a carbon atom, e.g. cyclohexyl-lithium, with a di(organooxy)-alkaline earth metal reactant, e.g. di-n-butoxy-magnesium, in an organic solvent at about -20.degree. to +120.degree.C. The organo-alkali metal reactant can be prepared by reacting an organo halide with an alkali metal, and this can be done in situ, i.e. in the presence of the di(organooxy)-alkaline earth metal reactant. The organometallic product has approximately the same chemical reactivity as the organo-alkali metal reactant from which it is prepared, but is more soluble in hydrocarbon solvents.

  一种含有碱金属的有机金属产物，其可溶于烃类溶剂，是通过在有机溶剂中将含有碳原子的碱金属有机反应物与二（有机氧基）碱土金属反应物反应制备而成，例如环己基锂与二正丁氧基镁，在约-20°C至+120°C的温度下反应。有机碱金属反应物可以通过有机卤化物与碱金属反应制备，而且这可以在原地完成，即在二（有机氧基）碱土金属反应物的存在下进行。这种有机金属产物与其制备的碱金属有机反应物具有大致相同的化学反应性，但在烃类溶剂中更易溶解。