methyl (2S,5R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl (2S,5R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
• 化学式: C₁₂H₂₁NO₉
• 分子量: 323.3
• InChiKey: BKZQMWNJESHHSA-IPKRQFAESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.1
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  166
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• [EN] PRODUCTION OF 6'-O-SIALYLLACTOSE AND INTERMEDIATES<br/>[FR] PRODUCTION DE 6'-O-SIALYLLACTOSE ET INTERMÉDIAIRES
  申请人：GLYCOM AS

  公开号：WO2011100979A1

  公开（公告）日：2011-08-25

  The present invention relates to a method for preparation of the trisaccharide 6'-0-sialyllactose (formula (I)) or salts thereof as well as intermediates in the synthesis and for the use of 6'-0-sialyllactose salts in pharmaceutical or nutritional compositions.

  本发明涉及一种制备三糖6'-0-唾液酸乳糖苷（化学式（I））或其盐的方法，以及合成中间体和将6'-0-唾液酸乳糖苷盐用于药用或营养组合物的用途。
• Remodelling and glycoconjugation of Fibroblast Growth Factor (FGF)
  申请人：BioGeneriX AG

  公开号：EP2279755A2

  公开（公告）日：2011-02-02

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.

  本发明包括重塑肽分子的方法和组合物，包括在肽上添加或删除一个或多个糖基，和/或在肽上添加修饰基团。
• Remodeling and glycoconjugation of Factor IX
  申请人：NOVO NORDISK A/S

  公开号：EP2322229B1

  公开（公告）日：2016-12-21
• Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
  申请人：DeFrees Shawn

  公开号：US20080050772A1

  公开（公告）日：2008-02-28

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
• Glycoconjugation methods and proteins/peptides produced by the methods
  申请人：DeFrees Shawn

  公开号：US20080146494A1

  公开（公告）日：2008-06-19

  The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.