methyl N-[(E)-5-[6-hydroxy-5-[(2E,4E,9Z,13E)-8-hydroxy-2,5,9-trimethylpentadeca-2,4,9,13-tetraenoyl]-4-oxopyran-2-yl]hex-1-enyl]carbamate

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl N-[(E)-5-[6-hydroxy-5-[(2E,4E,9Z,13E)-8-hydroxy-2,5,9-trimethylpentadeca-2,4,9,13-tetraenoyl]-4-oxopyran-2-yl]hex-1-enyl]carbamate
• 化学式: C₃₁H₄₃NO₇
• 分子量: 541.7
• InChiKey: WXSGHDSVVDSQCP-SKFHZJMVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  39
• 可旋转键数：
  16
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  122
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• Compounds for use in the treatment of filariasis
  申请人：Rheinische Friedrich-Wilhelms-Universität Bonn

  公开号：EP2520293A1

  公开（公告）日：2012-11-07

  The present invention relates to compounds according to the general formula (1) for use in the therapeutic or prophylactic treatment of filariasis, a nematicidal composition comprising as an active ingredient a compound according to the general formula (1), and a method for treating filariasis.

  本发明涉及用于丝虫病治疗或预防的通式（1）化合物、包含通式（1）化合物作为活性成分的杀线虫组合物，以及治疗丝虫病的方法。
• [EN] SOLID AND LIQUISOLID FORMULATIONS OF CORALLOPYRONIN A<br/>[FR] FORMULATIONS SOLIDES ET LIQUISOLIDES DE LA CORALLOPYRONINE A
  申请人：UNIV BONN RHEINISCHE FRIEDRICH WILHELMS

  公开号：WO2021219808A1

  公开（公告）日：2021-11-04

  The present invention relates to a solid or liquisolid formulation comprising corallopyronin A, wherein the formulation comprises an amorphous solid dispersion of corallopyronin A embedded in a water-soluble polymer or corallopyronin A loaded onto porous silica.