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1-Hexadecoxyoctadecane

中文名称
——
中文别名
——
英文名称
1-Hexadecoxyoctadecane
英文别名
——
1-Hexadecoxyoctadecane化学式
CAS
——
化学式
C34H70O
mdl
——
分子量
494.9
InChiKey
OUUCZGCOAXRCHN-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    16.7
  • 重原子数:
    35
  • 可旋转键数:
    32
  • 环数:
    0.0
  • sp3杂化的碳原子比例:
    1.0
  • 拓扑面积:
    9.2
  • 氢给体数:
    0
  • 氢受体数:
    1

文献信息

  • [EN] ISOTHIAZOLOQUINOLONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS<br/>[FR] ANTI-INFECTIEUX A BASE D'ISOTHIAZOLOQUINOLONES ET DE SELS CORRESPONDANTS
    申请人:ACHILLION PHARMACEUTICALS INC
    公开号:WO2005019228A1
    公开(公告)日:2005-03-03
    The invention provides compounds and salts of Formula (I) and Formula (II): which possess antimicrobial activity. The invention also provides novel synthetic intermediates useful in making compounds of Formula (I) and Formula (II). The variables A1, R2, R3, R5, R6, R7, A8 and R9 are defined herein. Certain compounds of Formula (I) and Formula (II) disclosed herein are potent and selective inhibitors of bacterial DNA synthesis and bacterial replication. The invention also provides antimicrobial compositions, including pharmaceutical compositions, containing one or more compounds of Formula (I) or Formula (II) and one or more carriers, excipients, or diluents. Such compositions may contain a compound of Formula (I) or Formula (II) as the only active agent or may contain a combination of a compound of Formula (I) or Formula (II) and one or more other active agents. The invention also provides methods for treating microbial infections in animals.
    本发明提供了具有抗菌活性的公式(I)和公式(II)的化合物及盐类:本发明还提供了用于制造公式(I)和公式(II)化合物的新的合成中间体。变量A1、R2、R3、R5、R6、R7、A8和R9在此文中定义。本文披露的某些公式(I)和公式(II)化合物是细菌DNA合成和细菌复制的强效和选择性抑制剂。本发明还提供了含有一种或多种公式(I)或公式(II)化合物以及一种或多种载体、辅料或稀释剂的抗菌组合物,包括药物组合物。这样的组合物可以只含有公式(I)或公式(II)的化合物作为唯一的活性成分,也可以含有公式(I)或公式(II)的化合物与一种或多种其他活性成分的组合。本发明还提供了用于治疗动物微生物感染的方法。
  • [EN] CONTROLLED-DELIVERY CROMAKALIM PRODRUGS<br/>[FR] PROMÉDICAMENTS DE CROMAKALIM À LIBÉRATION CONTRÔLÉE
    申请人:QLARIS BIO INC
    公开号:WO2021119503A1
    公开(公告)日:2021-06-17
    The present invention provides cromakalim prodrugs, compositions, and their use for the modulation of ATP-sensitive potassium (KATP) channels for therapeutic purposes.
    本发明提供了克罗马卡利姆前药、组合物及其用于调节ATP敏感性(KATP)通道以用于治疗目的的方法。
  • Substituted 1,2-ethylenediamines, Methods for Preparing Them and Uses Thereof
    申请人:Eickmeier Christian
    公开号:US20060223759A1
    公开(公告)日:2006-10-05
    The present invention relates to substituted 1,2-ethylenediamines of general formula (I) wherein the groups R 1 to R 15 , A, B, L, i as well as X 1 -X 4 are defined as in the specification and claims and the use thereof for the treatment of Alzheimer's disease (AD) and similar diseases.
    本发明涉及通式(I)的取代1,2-乙二胺化合物,其中基团R1至R15,A,B,L,i以及X1-X4如规范和权利要求中所定义,并且其用于治疗阿尔茨海默病(AD)和类似疾病。
  • [EN] 5-ALKYLTHIO-7-[(4-ARYLBENZYL)AMINO]-1(2)H-PYRAZOLO[4,3-D]PYRIMIDINES FOR TREATMENT OF LYMPHOMA<br/>[FR] 5-ALKYLTHIO-7-[(4-ARYLBENZYL) AMINO] -1 (2) H-PYRAZOLO [4,3-D] PYRIMIDINES POUR LE TRAITEMENT DU LYMPHOME
    申请人:UNIV PALACKEHO
    公开号:WO2019149295A1
    公开(公告)日:2019-08-08
    The present invention relates to 5-alkylthio-7-[(4-arylbenzyl)amino]-1(2)H-pyrazolo[4,3-d]pyrimidine derivatives of formula I which are effective inhibitors of kinases and exhibit strong antiproliferative and proapoptotic properties on lymphoma cells. This invention further relates to use of said derivatives in the treatment of blood hyperproliferative diseases, such as Non-Hodgkin lymphomas.
    本发明涉及式I的5-烷基基-7-[(4-芳基苄基)基]-1(2)H-吡唑并[4,3-d]嘧啶生物,它们是激酶的有效抑制剂,并在淋巴瘤细胞上表现出强烈的抗增殖和促凋亡特性。本发明还涉及利用这些衍生物治疗血液过度增殖性疾病,如非霍奇淋巴瘤。
  • Modified amino acids, pharmaceuticals containing these compounds and method for their production
    申请人:——
    公开号:US20010036946A1
    公开(公告)日:2001-11-01
    The present invention relates to modified amino acids of general formula 1 wherein A, Z, X, n, m, R, R 2 , R 3 , R 4 and R 11 are defined as in claims 1 to 5 , their tautomers, their diastereomers, their enantiomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, pharmaceutical compositions containing these compounds, the use thereof and processes for preparing them as well as their use for the production and purification of antibodies and as labelled compounds in RIA- and ELISA assays and as diagnostic or analytical aids in neurotransmitter research.
    本发明涉及一般式1的改良氨基酸,其中A、Z、X、n、m、R、R2、R3、R4和R11如权利要求1至5中所定义,它们的互变异构体、对映异构体、混合物及其盐,特别是其与无机或有机酸或碱的生理上可接受的盐,含有这些化合物的药物组合物,其用途以及用于制备它们的过程,以及它们在抗体的生产和纯化中的用途,以及在RIA和ELISA测定中作为标记化合物以及在神经递质研究中作为诊断或分析辅助工具的用途。
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