1-(5-amino-2-hydroxy-phenyl)-butan-1-one | 99075-34-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(5-amino-2-hydroxy-phenyl)-butan-1-one
• 英文别名: 1-(5-Amino-2-hydroxy-phenyl)-butan-1-on；N-butyryl-p-aminophenol；1-(5-Amino-2-hydroxyphenyl)butan-1-one
• CAS: 99075-34-0
• 化学式: C₁₀H₁₃NO₂
• 分子量: 179.219
• InChiKey: ZAGDPJLIYOUBIB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  acetaminophen butyrate 在 三氯化铝 作用下， 生成 1-(5-amino-2-hydroxy-phenyl)-butan-1-one
  参考文献：
  名称：

  Iorio, Annali di Chimica, 1959, vol. 49, p. 370,374

  摘要：

  DOI：

文献信息

• Analgesics, anaesthetics, antifoulants, aversants, irritants, incapacitants and compositions containing the same
  申请人：Blum Mel

  公开号：US20070225515A1

  公开（公告）日：2007-09-27

  Compounds and compositions the same. Method of making the compounds. The compounds and/or compositions used as an analgesic, anaesthetic, antifoulant, aversant, irritant, sternutator, neurodegenerator, counter irritant (delayed), rubifaciant, stomachic, fungicide, insecticide, preservative, circulatory stimulant, cardio-protective agent, immune booster, decongestant, anti-inflammatory agent, incapacitant, biocide, mildewcide, pharmaceutical, repellent, flavorant, carminative, antismoking agent, and/or antithrombotic agent. One of the compounds being lidocaine nonivamide. The compositions comprising one or more of: the compounds, one or more of an antioxidant, a UV absorber, and one or more biocides such as, for example, OBPA.

  化合物和组合物相同。制备这些化合物的方法。这些化合物和/或组合物用作止痛剂、麻醉剂、防污剂、驱避剂、刺激剂、喷鼻剂、神经变性剂、延迟性刺激剂、红斑剂、胃药、杀真菌剂、杀虫剂、防腐剂、循环刺激剂、心脏保护剂、免疫增强剂、通窍剂、抗炎剂、致残剂、生物杀灭剂、霉菌杀灭剂、药用、驱虫剂、调味剂、驱风剂、抗吸烟剂和/或抗血栓剂。其中一种化合物是利多卡因辛烷酸酯。组合物包括：这些化合物中的一种或多种、一种或多种抗氧化剂、一种或多种紫外线吸收剂，以及一种或多种生物杀灭剂，例如OBPA。
• Compositions containing antimicrobial agents in combination with stabilizers
  申请人：MORTON THIOKOL, INC.

  公开号：EP0218768A2

  公开（公告）日：1987-04-22

  Composition of an antimicrobial agent and an antioxidant having improved antimicrobial activity compared to the antimicrobial agent alone. The preferred environment of the invention is a composition of a thermoplastic resin, an antioxidant, and an antimicrobial agent, the latter two being compatible with the resin. The resin composition can contain other usual additives, and can be melt processed at an elevated temperature to form articles such as films or fibres having improved antimicrobial activity. A method for improving the efficacy of an antimicrobial agent by combining it with an antioxidant is disclosed. A method for melt- processing a resin composition containing an antimicrobial material is also dsiclosed, wherein the resin composition includes an antioxidant.

  一种抗菌剂和一种抗氧化剂的组合物，与单独使用抗菌剂相比，其抗菌活性有所提高。本发明的优选环境是一种由热塑性树脂、抗氧化剂和抗菌剂组成的组合物，后两者与树脂相容。该树脂组合物可以含有其他常用添加剂，并可以在高温下进行熔融加工，以形成具有更好抗菌活性的薄膜或纤维等物品。本发明公开了一种通过将抗菌剂与抗氧化剂结合来提高抗菌剂功效的方法。还公开了一种熔融加工含有抗菌材料的树脂组合物的方法，其中树脂组合物包括抗氧化剂。
• Improved process for preparing acyl aminophenols
  申请人：HOECHST CELANESE CORPORATION

  公开号：EP0622354A2

  公开（公告）日：1994-11-02

  A process for the production of N-acylaminophenols by the concurrent hydrogenation of a nitrophenol to an aminophenol and the acylation of the aminophenol with acyl anhydride takes place on a continuous basis in a stirred tank reactor in which liquid product is continuously withdrawn from the reactor. Of particular interest is the manufacture of acetaminophen, N-acetyl-p-aminophenol by continuous reaction of p-ntirophenol, hydrogen and acetic anhydride.

  一种通过硝基苯酚同时氢化为氨基苯酚，氨基苯酚同时与酰基酸酐酰化来生产 N-酰基氨基苯酚的工艺是在搅拌罐反应器中连续进行的，在该反应器中液体产品被不断地从反应器中抽出。特别令人感兴趣的是通过对硝基苯酚、氢和乙酸酐的连续反应制造对乙酰氨基酚、N-乙酰基对氨基苯酚。
• Optical Film, Manufacturing Method for Optical Film, Polarizing Plate and Liquid Crystal Display Device
  申请人：Umeda Hiroki

  公开号：US20100239789A1

  公开（公告）日：2010-09-23

  A manufacturing method for an optical film via a solution casting method on a transparent substrate film comprising the steps of: (i) ejecting a micro-particle dispersion containing micro-particles having a average particle diameter of at least 25-200 nm as liquid droplets by use of an ink-jet head when a residual solvent content in a web is 5-400 weight %, and (ii) depositing the liquid droplets to adhere onto one side surface of a web and to form a micro convex structure, and further to form 1-10,000 points of convex parts per 10,000 we having a height of the convex parts of the convex structure of 0.01-0.5 μm.
• US4077807A
  申请人：——

  公开号：US4077807A

  公开（公告）日：1978-03-07