3-Aceto-2-aminobenzoesaeure | 53589-26-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Aceto-2-aminobenzoesaeure
• 英文别名: acetylanthranilic acid；Acetyl-o-aminobenzoesaure；3-acetyl-2-aminobenzoic acid
• CAS: 53589-26-7
• 化学式: C₉H₉NO₃
• 分子量: 179.175
• InChiKey: GSVGAXFEIRLBIG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  80.4
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-Aceto-2-aminobenzoesaeure 、 3-amino-9-methoxy-1-phenyl-6,7-dihydro-3H-[1,4]diazepino[6,7,1-hi]indol-4-one 在 anhydrous phosphorus trichloride 、 碳酸氢钠 作用下， 以 二氯甲烷 为溶剂， 生成 9-Methoxy-3-(2-methyl-4-oxo-4H-quinazolin-3yl)-1-phenyl-6,7-dihydro-3H-[1,4]diazepino[6,7,1-hi]indol-4-one
  参考文献：
  名称：

  Phosphodiesterase 4-inhibiting diazepinoindolones

  摘要：

  本发明提供了抑制磷酸二酯酶4的化合物，其具有化学式(I)。本发明还提供了利用化合物化学式(I)预防或治疗哮喘、特应性皮炎、类风湿性关节炎、炎症性肠道疾病、肺动脉高压、肝损伤、骨质流失、脓毒性休克或多发性硬化症的方法，以及含有化合物化学式(I)的药物组合物。

  公开号：

  US06239130B1

文献信息

• Wellbore fluids comprising mineral particles and methods relating thereto
  申请人：Halliburton Energy Services, Inc.

  公开号：US10407988B2

  公开（公告）日：2019-09-10

  Mineral particles may provide for wellbore fluids with tailorable properties and capabilities. Methods of using mineral particles may include circulating a wellbore fluid with a first density of about 7 ppg to about 50 ppg in a wellbore penetrating a subterranean formation, the wellbore fluid comprising a base fluid, a plurality of first mineral particles, and a plurality of second mineral particles such that the first mineral particles and the second mineral particles are present in a first relative ratio, and the first mineral particles and the second mineral particles having a multiparticle specific gravity of about 3 to about 20; and changing the first relative ratio to a second relative ratio on-the-fly so as to yield the wellbore fluid with a second density.

  矿物颗粒可提供具有可定制特性和能力的井筒流体。使用矿物颗粒的方法可包括在穿透地下地层的井筒中循环第一密度约为 7 ppg 至约 50 ppg 的井筒流体，井筒流体包括基础流体、多个第一矿物颗粒和多个第二矿物颗粒，第一矿物颗粒和第二矿物颗粒以第一相对比存在，第一矿物颗粒和第二矿物颗粒的多颗粒比重约为 3 至约 20；并将第一相对比率即时改变为第二相对比率，以产生具有第二密度的井筒流体。
• Process for obtaining a scented extract of fresh flowers and/or leaves using natural solvents
  申请人：Lavoine-Hanneguelle Sophie

  公开号：US10577561B2

  公开（公告）日：2020-03-03

  The invention relates to methods for obtaining a scented extract from fresh flowers, flowering heads and/or leaves of a moist plant. The method includes picking the flowers, flowering tops and/or leaves of the plant and infusing them in at least one bath comprising an alcoholic solvent, at a temperature below 50° C., to obtain an alcoholic mixture. The alcoholic mixture is then filtered to recover an alcoholic floral infusion. The method also includes performing a supercritical CO2 extraction of the alcoholic floral infusion to obtain a scented extract. This scented extract has an alcohol titrate of at least 75%. The invention also relates to scented water or perfume, food flavoring, and cosmetic compositions that contain the scented extract as an ingredient.

  本发明涉及从潮湿植物的鲜花、花头和/或叶片中获得芳香提取物的方法。该方法包括采摘植物的花、花头和/或叶，并将其浸泡在至少一个含有酒精溶剂的浴槽中，温度低于 50 摄氏度，以获得酒精混合物。然后过滤酒精混合物，以回收酒精花卉浸泡液。该方法还包括对酒精花香浸液进行超临界二氧化碳萃取，以获得香味萃取物。这种香味提取物的酒精滴定度至少为 75%。本发明还涉及香味水或香水、食品调味料以及含有香味提取物作为成分的化妆品组合物。
• PHOTOCLEAVABLE AGENTS AND CONJUGATES FOR THE DETECTION AND ISOLATION OF BIOMOLECULES
  申请人：TRUSTEES OF BOSTON UNIVERSITY

  公开号：EP0763009A1

  公开（公告）日：1997-03-19
• EP0763009A4
  申请人：——

  公开号：EP0763009A4

  公开（公告）日：1998-05-06
• PHOSPHODIESTERASE 4-INHIBITING DIAZEPINOINDOLONES
  申请人：PARKE-DAVIS

  公开号：EP0980374A1

  公开（公告）日：2000-02-23