申请人:Ripin H. B. David
公开号:US20050026940A1
公开(公告)日:2005-02-03
The invention relates to processes for preparing compounds of the formula 1
and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R
1
, R
3
, R
4
, R
6
, R
11
, R
13
, R
14
, R
15
, R
16
, R
17
, k, l, and m are as defined herein. The compounds of formula 1 are useful intermediates toward preparing compounds that may be used in treating abnormal cell growth in mammals by administering pharmaceutical compositions.
本发明涉及制备式1化合物的过程,以及其药学上可接受的盐、前药和溶剂化物,其中R1、R3、R4、R6、R11、R13、R14、R15、R16、R17、k、l和m的定义如本文所述。式1化合物是制备可用于治疗哺乳动物异常细胞生长的化合物的有用中间体,通过给药药物组合物。