An active substance-containing polymer gel characterized by comprising an active substance with an anionic substituent thereon, held by a copolymer gel through adsorption therein, said copolymer gel being prepared by copolymerization of a monomer mixture containing at least a hydrocarbon group-containing (meth) acrylate which has one or more hydroxyl groups and has optionally an intramolecular ether linkage, and a monomer with a quaternary ammonium salt on the side chain is capable of strongly holding in the copolymer gel, the anionic functional group-containing active substance to produce a significant sustained release effect and of being worked into any desired form in an extremely easy manner.
一种含活性物质的聚合物凝胶,其特征在于包含一种活性物质,该活性物质带有阴离子取代基,通过吸附作用被共聚物凝胶吸附,所述共聚物凝胶是通过共聚单体混合物制备的,该单体混合物至少含有一种含烃基的(甲基)
丙烯酸酯,该
丙烯酸酯具有一个或多个羟基,并可选择具有分子内醚键、侧链上带有季
铵盐的单体能够在共聚凝胶中强力保持含有阴离子官能团的活性物质,以产生显著的持续释放效果,并能以极其简便的方式加工成任何所需的形式。