3-Hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-3-methylbutan-1-one | 220183-80-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-Hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-3-methylbutan-1-one
• CAS: 220183-80-2
• 化学式: C₁₃H₁₈O₄
• 分子量: 238.28
• InChiKey: JHKMRRUVNXCXNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] FUNCTIONALIZED POLYMERS USING PROTECTED THIOLS<br/>[FR] POLYMÈRES FONCTIONNALISÉS UTILISANT DES THIOLS PROTÉGÉS
  申请人：CALIFORNIA INST OF TECHN

  公开号：WO2009052148A1

  公开（公告）日：2009-04-23

  A process for the preparation of functional molecules using the thiol-ene coupling reaction and a process for the preparation of protected functional thiols, specifically thioesters is provided. The methods may be used to make functional polymers and other molecules. The method of making a functionalized polymer using a thiol-ene reaction comprises: providing a functionalized thioester having the following formula: (I) wherein R is a functional group and COR' is a protecting group; cleaving the functionalized thioester, forming a functional thiol and an acyl group; providing a polymer having a pendant vinyl group; and reacting the polymer with the functional thiol whereby a functionalized polymer is formed, wherein the functional thiol is not isolated prior to reacting with the polymer.

  提供了一种利用硫醇-烯烃偶联反应制备功能分子的方法，以及一种制备受保护的功能硫醇，特别是硫酯的方法。这些方法可用于制备功能聚合物和其他分子。利用硫醇-烯烃反应制备功能化聚合物的方法包括：提供具有以下结构式的功能化硫酯：(I)，其中R是功能基团，COR'是保护基团；裂解功能化硫酯，形成功能硫醇和酰基；提供具有一个侧链乙烯基团的聚合物；将聚合物与功能硫醇反应，从而形成功能化聚合物，其中在与聚合物反应之前未将功能硫醇分离出来。
• Polymerized hydrogel adhesives with low levels of monomer units in salt form
  申请人：The Procter & Gamble Company

  公开号：US20040115251A1

  公开（公告）日：2004-06-17

  The present invention relates to hydrogel adhesives for attachment to mammalian skin which exhibit particularly good attachment in excess moisture conditions, through the solution of the rheology conditions and level of monomers in salt form. According to a specific embodiment of the present invention, hydrogel compositions are provided, which provide particularly good peel strength and cohesiveness properties; through the selection of monomer unit type of degrees of neutralization. The present invention also encompasses personal care products containing the active adhesives, such as disposable waste management articles, disposable absorbent articles, and various functional articles for attachment to the human body.

  本发明涉及用于附着于哺乳动物皮肤的水凝胶粘合剂，其在过多湿润条件下表现出特别良好的附着性，通过解决流变条件和盐形态单体水平。根据本发明的一个具体实施例，提供了水凝胶组合物，其提供特别良好的剥离强度和内聚性能；通过选择单体单元类型和中和度。本发明还涵盖了含有活性粘合剂的个人护理产品，如一次性废物管理用品、一次性吸收用品以及各种用于附着于人体的功能性用品。
• Stable, cationically polymerizable/crosslinkable dental compositions having high filler contents
  申请人：Frances Jean-Marc

  公开号：US20050059752A1

  公开（公告）日：2005-03-17

  Stable, highly filled cationic dental compositions useful for the production of dental prostheses and dental restoration materials contain: (1) at least one compound which is reactive cationically when activated, advantageously at least one UV-and cationically reactive oxirane-functionalized silicone; (2) at least one dental filler, advantageously SiO 2 ; (3) at least one organic polymer or copolymer dispersant having an amine index less than or equal to 100 mg of potassium hydroxide per gram of dispersant, advantageously a polyurethane/acrylate copolymer or alkylammonium salt thereof; (4) at least one cationic photoinitiator, advantageously iodonium borate; and (5) optionally, at least one photosensitizer.

  稳定、高填充的阳离子牙科组合物，可用于制备牙科义齿和牙科修复材料，包含：(1)至少一种在激活时具有阳离子反应性的化合物，有利的是至少一种紫外线和阳离子反应性环氧基硅烷；(2)至少一种牙科填料，有利的是SiO2；(3)至少一种有机聚合物或共聚物分散剂，其胺指数小于或等于100毫克氢氧化钾/克分散剂，有利的是聚氨酯/丙烯酸酯共聚物或其烷基铵盐；(4)至少一种阳离子光引发剂，有利的是碘酸盐；(5)可选地，至少一种光敏剂。
• Functionalized Polymers Using Protected Thiols
  申请人：David Ralph L.

  公开号：US20110077407A1

  公开（公告）日：2011-03-31

  A process for the preparation of functional molecules using the thiol-ene coupling reaction and a process for the preparation of protected functional thiols, specifically thioesters is provided. The methods may be used to make functional polymers and other molecules. The method of making a functionalized polymer using a thiol-ene reaction comprises: providing a functionalized thioester having the following formula: wherein R is a functional group and COR′ is a protecting group; cleaving the functionalized thioester, forming a functional thiol and an acyl group; providing a polymer having a pendant vinyl group; and reacting the polymer with the functional thiol whereby a functionalized polymer is formed, wherein the functional thiol is not isolated prior to reacting with the polymer.

  提供了一种使用硫醇-烯烃偶联反应制备功能分子的过程和一种制备受保护的功能硫醇，特别是硫酯的过程。这些方法可用于制备功能性聚合物和其他分子。使用硫醇-烯烃反应制备功能化聚合物的方法包括：提供具有以下式的功能化硫酯： 其中，R是功能基团，COR'是保护基团；裂解功能化硫酯，形成功能硫醇和酰基；提供具有侧链乙烯基团的聚合物；将聚合物与功能性硫醇反应，从而形成功能化聚合物，其中在与聚合物反应之前未分离功能性硫醇。
• Dental composition based on silicone crosslinkable by cation process
  申请人：Frances Jean-Marc

  公开号：US20060178444A1

  公开（公告）日：2006-08-10

  The invention concerns dental compositions. Said composition comprises (1) a silicone crosslinkable and/or polymerizable by cationic process; (2) an efficient amount of at least an initiator such as an organometallic complex borate; and (3) a dental filler present in the composition in a proportion of at least 10 wt. % relative to the composition total weight. Said dental compositions are useful for making dental prostheses or for dental restoration.

  该发明涉及牙科组合物。该组合物包括（1）通过阳离子过程交联和/或聚合的硅烷；（2）至少一种启动剂，例如有机金属配合物硼酸盐的有效量；以及（3）牙科填料，其在组合物总重量中的比例至少为10 wt.％。该牙科组合物可用于制作牙科义齿或进行牙齿修复。