(2S,3R,4S,5S,6R)-6-Hydroxymethyl-3-tetradecyloxy-tetrahydro-pyran-2,4,5-triol | 142025-89-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3R,4S,5S,6R)-6-Hydroxymethyl-3-tetradecyloxy-tetrahydro-pyran-2,4,5-triol
• 英文别名: (2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3-tetradecoxyoxane-2,4,5-triol
• CAS: 142025-89-6
• 化学式: C₂₀H₄₀O₆
• 分子量: 376.534
• InChiKey: YLBUIXJXVBDIME-OBKDMQGPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  26
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE
  申请人：NESTOR John J.

  公开号：US20140349928A1

  公开（公告）日：2014-11-27

  Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.

  本文描述了共价修饰肽和/或蛋白质的合成方法和治疗用途。共价修饰的肽和/或蛋白质可以提高基于肽和蛋白质的治疗药物的药理特性。
• IMPROVED PEPTIDE PHARMACEUTICALS
  申请人：EUMEDERIS PHARMACEUTICALS, INC.

  公开号：US20150307550A1

  公开（公告）日：2015-10-29

  Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.

  本文描述了共价修饰肽和/或蛋白质的合成方法和治疗用途。共价修饰的肽和/或蛋白质可以改善基于肽和蛋白质的治疗药物的药理特性。
• Peptide Pharmaceuticals
  申请人：EuMederis Pharmaceuticals, Inc.

  公开号：US20150031630A1

  公开（公告）日：2015-01-29

  Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.

  本文描述了共价修饰肽和/或蛋白质的合成方法和治疗用途。共价修饰的肽和/或蛋白质可以改善基于肽和蛋白质的治疗药物的药理特性。
• Peptide pharmaceuticals
  申请人：EUMEDERIS PHARMACEUTICALS, INC.

  公开号：US10005817B2

  公开（公告）日：2018-06-26

  Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.

  本文描述了共价修饰肽和/或蛋白质的合成方法和治疗用途。共价修饰的肽和/或蛋白质可改善基于肽和蛋白质的疗法的药物特性。
• Peptide pharmaceuticals for insulin resistance
  申请人：Nestor John J.

  公开号：US10471127B2

  公开（公告）日：2019-11-12

  Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.

  本文描述了共价修饰肽和/或蛋白质的合成方法和治疗用途。共价修饰的肽和/或蛋白质可改善基于肽和蛋白质的疗法的药物特性。