[(5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methanol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: [(5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methanol
• 化学式: C₇H₁₄O₄
• 分子量: 162.18
• InChiKey: INVRLGIKFANLFP-LWOQYNTDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• SYNTHESIS OF MACROCYCLIC CANCER CHEMOTHERAPY AGENTS AND METHODS OF USE
  申请人：Ghosh Arun K

  公开号：US20110028540A1

  公开（公告）日：2011-02-03

  Herein are described a process for forming a quaternary carbon useful in the preparation of macrolactones, an enantioselective synthesis of (+)-peloruside A, and methods for treating a patient in need of relief from cancer or a cancer-related disease. The described processes are useful for preparing compounds containing quaternary carbons, including structural analogs and derivatives of peloruside A.
• US8580975B2
  申请人：——

  公开号：US8580975B2

  公开（公告）日：2013-11-12