(3R,4S,5R,6R)-2-[(6-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (3R,4S,5R,6R)-2-[(6-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• 化学式: C₁₄H₁₆ClNO₆
• 分子量: 329.73
• InChiKey: OQWBAXBVBGNSPW-RRYROLNDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  115
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• NUTRITIONAL MIXTURE AND METHOD FOR EARLY IDENTIFICATION AND COUNT OF GRAM-NEGATIVE ORGANISMS
  申请人：Centro Nacional de Biopreparados

  公开号：EP1300471A1

  公开（公告）日：2003-04-09

  The present invention is related with Microbiology and particularly with a nutrient mixture and a procedure for the identification and the early count of Gram-negative organisms. This mixture allows the development of five different colony colors in the organisms to be detected, and the appearance of three colored fluorescent emissions, the appearance of three different colors halos and zones with opaque precipitates surrounding such colonies. Those factors, together with the color changes in the medium, allow a differentiation with a high sensibility and specificity level. The mixture include specific relations of the mixtures of tryptophan rich protein fractions, free tryptophan, organic or inorganic salts, color or fluorescence providing substances, cellulose and hemi cellulose and other components which provide from 1 to 2 layers in the composition.

  本发明与微生物学有关，特别是与一种营养混合物和一种用于鉴定和早期计数革兰氏阴性生物的程序有关。这种混合物可以使要检测的生物体呈现出五种不同的菌落颜色，出现三种不同颜色的荧光发射，出现三种不同颜色的光晕和菌落周围有不透明沉淀物的区域。这些因素加上培养基中的颜色变化，可以实现高灵敏度和高特异性的区分。 混合物包括富含色氨酸的蛋白质组分、游离色氨酸、有机或无机盐、提供颜色或荧光的物质、纤维素和半纤维素及其他成分的混合物的特定关系，在组成中提供 1 至 2 层。
• Nutritional mixture and method for early identification and count of gram-negative organisms
  申请人：——

  公开号：US20030170773A1

  公开（公告）日：2003-09-11

  The present invention is related with Microbiology and particularly with a nutrient mixture and a procedure for the identification and the early count of Gram-negative organisms. This mixture allows the development of five different colony colors in the organisms to be detected, and the appearance of three colored fluorescent emissions, the appearance of three different colors halos and zones with opaque precipitates surrounding such colonies. Those factors, together with the color changes in the medium, allow a differentiation with a high sensibility and specificity level. The mixture include specific relations of the mixtures of tryptophan rich protein fractions, free tryptophan, organic or inorganic salts, color or fluorescence providing substances, cellulose and hemi cellulose and other components which provide from 1 to 2 layers in the composition.

  本发明与微生物学有关，特别是与一种营养混合物和一种用于鉴定和早期计数革兰氏阴性生物的程序有关。这种混合物可以使要检测的生物体呈现出五种不同的菌落颜色，出现三种不同颜色的荧光发射，出现三种不同颜色的光晕和菌落周围有不透明沉淀物的区域。这些因素加上培养基中的颜色变化，可以实现高灵敏度和高特异性的区分。 混合物包括富含色氨酸的蛋白质组分、游离色氨酸、有机或无机盐、提供颜色或荧光的物质、纤维素和半纤维素及其他成分的混合物的特定关系，在组成中提供 1 至 2 层。
• Diagnostic method for bacterial vaginosis based on detecting antibodies against gvh toxin of gardnerella vaginalis
  申请人：——

  公开号：US20040101918A1

  公开（公告）日：2004-05-27

  The current invention relates to a method for the determination of the risk of pathologies in a population of women colonized by the Gardnerella vaginalis bacterium, comprising the following steps in order: a) determination of the IgA and/or IgG and/or IgM antibody levels against Gvh toxin secreted by G. vaginalis in a sample of body fluid; b) comparison of said levels of IgA and/or IgG and/or IgM with predeterminate levels of IgA and/or IgG and/or IgM, respectively; c) determination of the risk factor. Said method resulted particularly efficient in permitting to obtain an accurate and reliable evaluation of the risk of pathologies related to the colonization by the bacterium G. vaginalis in women. Consequently, this method gives the physician an effective tool to decide whether or not to administer a pharmacological therapy.

  本发明涉及一种方法，用于确定被阴道加德纳菌定植的妇女群体的病变风险。 阴道加德纳菌 该方法依次包括以下步骤： a) 测定针对阴道加德纳菌分泌的 Gvh 毒素的 IgA 和/或 IgG 和/或 IgM 抗体水平，包括 阴道加德纳菌 体液样本中针对阴道杆菌分泌的 Gvh 毒素的 IgA 和/或 IgG 和/或 IgM 抗体水平 b) 将上述 IgA 和/或 IgG 和/或 IgM 水平分别与预先确定的 IgA 和/或 IgG 和/或 IgM 水平进行比较； c) 确定风险因素。 该方法特别有效，能准确可靠地评估与阴道杆菌定植有关的病理风险。 阴道杆菌 的风险。因此，这种方法为医生提供了一个有效的工具来决定是否进行药物治疗。
• PROCEDE D'IDENTIFICATION DE MICROORGANISMES AVEC AU MOINS DEUX CHROMOGENES
  申请人：Rambach, Alain

  公开号：EP0711360A1

  公开（公告）日：1996-05-15
• Procédé d'identification de microorganismes à l'aide d'au moins deux chromogènes
  申请人：Rambach, Alain

  公开号：EP0711360B1

  公开（公告）日：1998-03-11