(1S,4S,6R)-4-isopropenyl-1-methylbicyclo[4.4.0]decanespiro[5.1']cyclopenta-8,3'-dien-2-one | 1046789-49-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1S,4S,6R)-4-isopropenyl-1-methylbicyclo[4.4.0]decanespiro[5.1']cyclopenta-8,3'-dien-2-one
• 英文别名: (3S,4aR,8aS)-8a-methyl-3-prop-1-en-2-ylspiro[3,4a,5,8-tetrahydro-2H-naphthalene-4,4'-cyclopentene]-1-one
• CAS: 1046789-49-4
• 化学式: C₁₈H₂₄O
• 分子量: 256.388
• InChiKey: PUZRSWAZGCUUKB-ZOBUZTSGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (6R,7S,10S)-6,7-bisallyl-10-isopropenyl-7-methylspiro[4.5]dec-2-en-8-one 在 Grubbs catalyst first generation 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 以100%的产率得到(1S,4S,6R)-4-isopropenyl-1-methylbicyclo[4.4.0]decanespiro[5.1']cyclopenta-8,3'-dien-2-one
  参考文献：
  名称：

  A rapid and efficient enantiospecific synthesis of the functionalized ABC-ring system of tetranortriterpene dumsins and their analogues

  摘要：

  A rapid and enantiospecific synthesis of the ABC ring system of tetranortriterpene dumsin and its analogues, starting from the readily available monoterpene (R)-carvone employing two RCM reactions as key steps, is described. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2008.05.015

文献信息

• A rapid and efficient enantiospecific synthesis of the functionalized ABC-ring system of tetranortriterpene dumsins and their analogues
  作者：Adusumilli Srikrishna、Vijendra H. Pardeshi、Pinnu Thriveni

  DOI：10.1016/j.tetasy.2008.05.015

  日期：2008.6

  A rapid and enantiospecific synthesis of the ABC ring system of tetranortriterpene dumsin and its analogues, starting from the readily available monoterpene (R)-carvone employing two RCM reactions as key steps, is described. (C) 2008 Elsevier Ltd. All rights reserved.