2-Ethyl-1,4,7,10,13,16-hexaoxacyclooctadecane | 83585-74-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Ethyl-1,4,7,10,13,16-hexaoxacyclooctadecane
• CAS: 83585-74-4
• 化学式: C₁₄H₂₈O₆
• 分子量: 292.37
• InChiKey: CSDNXEHZXUQQRG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  55.4
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• FLUORESCENT AROMATIC SENSORS AND THEIR METHODS OF USE
  申请人：Meador Michael A.

  公开号：US20080242870A1

  公开（公告）日：2008-10-02

  Aromatic molecules that can be used as sensors are described. The aromatic sensors include a polycyclic aromatic hydrocarbon core with a five-membered imide rings fused to the core and at least two pendant aryl groups. The aromatic sensor molecules can detect target analytes or molecular strain as a result of changes in their fluorescence, in many cases with on-off behavior. Aromatic molecules that fluoresce at various frequencies can be prepared by altering the structure of the aromatic core or the substituents attached to it. The aromatic molecules can be used as sensors for various applications such as, for example, the detection of dangerous chemicals, biomedical diagnosis, and the detection of damage or strain in composite materials. Methods of preparing aromatic sensor molecules are also described.

  描述了可以用作传感器的芳香分子。这些芳香传感器包括一个多环芳烃核心，该核心上融合了一个五元咪唑环，并且至少有两个侧链芳基基团。这些芳香传感器分子可以通过它们的荧光变化来检测目标分析物或分子应变，许多情况下具有开关行为。可以通过改变芳香核心的结构或连接到其上的取代基来制备在不同频率下发出荧光的芳香分子。这些芳香分子可以用作各种应用的传感器，例如检测危险化学品、生物医学诊断以及复合材料中的损伤或应变的检测。还描述了制备芳香传感器分子的方法。
• Process for producing chemically functionalized nano graphene materials
  申请人：Zhamu Aruna

  公开号：US20130005917A1

  公开（公告）日：2013-01-03

  Provided in this invention is a process for producing chemically functionalized nano graphene materials, known as nano graphene platelets (NGPs), graphene nano sheets, or graphene nano ribbons. Subsequently, a polymer can be grafted to a functional group of the resulting functionalized graphene. In one preferred embodiment, the process comprises a step of mixing a starting nano graphene material having edges and two primary graphene surfaces, an azide or bi-radical compound, and an organic solvent in a reactor, and allowing a chemical reaction between the nano graphene material and the azide compound to proceed at a temperature for a length of time sufficient to produce the functionalized nano graphene material.

  本发明提供了一种生产化学功能化纳米石墨烯材料的方法，被称为纳米石墨烯片（NGPs）、石墨烯纳米片或石墨烯纳米带。随后，可以将聚合物嫁接到所得到的功能化石墨烯的功能基上。在一种首选实施方案中，该过程包括将具有边缘和两个主要石墨烯表面的起始纳米石墨烯材料、叠氮化合物或双自由基化合物以及有机溶剂混合在反应器中，并允许在足够时间和温度下进行纳米石墨烯材料和叠氮化合物之间的化学反应，以产生功能化的纳米石墨烯材料。
• COMPOUND HAVING FLUORESCENT CHROMOPHORE, ION CONCENTRATION SENSOR INCLUDING COMPOUND, REAGENT INCLUDING COMPOUND, REAGENT KIT PROVIDED WITH REAGENT, PRECURSOR OF COMPOUND, AND METHOD FOR SYNTHESIZING COMPOUND
  申请人：National University Corporation Hokkaido University

  公开号：EP2684881A1

  公开（公告）日：2014-01-15

  A compound of the present invention comprises a triazapentalene backbone represented by the general formula 1 below as a fluorescent chromophore.

  本发明的一种化合物由以下通式 1 所代表的三氮杂戊二烯骨架作为荧光发色团组成。
• FLUORESCENCE COMPOUND, ION CONCENTRATION SENSOR INCLUDING THE COMPOUND, REAGENT INCLUDING COMPOUND, REAGENT KIT PROVIDED WITH REAGENT, AND METHOD FOR SYNTHESIZING COMPOUND
  申请人：National University Corporation Hokkaido University

  公开号：EP2684881B1

  公开（公告）日：2018-11-28
• SMALL MOLECULE ANTAGONISTS OF BCL-2 FAMILY PROTEINS
  申请人：Wang Shaomeng

  公开号：US20090082424A1

  公开（公告）日：2009-03-26

  The present invention relates to naturally occurring and chemically synthesized small molecule antagonists of Bcl-2 family proteins. In particular, the present invention provides gossypol compounds (e.g., isomers, enantiomers, racemic compounds, metabolites, derivatives, pharmaceutically acceptable salts, in combination with acids or bases, and the like) and methods of using these compounds as antagonists of the anti-apoptotic effects of Bcl-2 family member proteins (e.g., Bcl-2, Bcl-X L , and the like). The present invention also provides compositions comprising gossypol compounds and optionally one or more additional therapeutic agents (e.g., anticancer/chemotherapeutic agents). The present invention also provides methods for treating diseases and pathologies (e.g., neoplastic diseases) comprising administering a composition comprising gossypol compounds and optionally one or more additional therapeutic agents (e.g., anticancer/chemotherapeutic agents) and/or techniques (e.g., radiation therapies, surgical interventions, and the like) to a subject or in vitro cells, tissues, and organs.