2-(4-chloro-2-fluoro-3-methoxyphenyl)-1,3,2-dioxaborinane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-(4-chloro-2-fluoro-3-methoxyphenyl)-1,3,2-dioxaborinane
• 化学式: C₁₀H₁₁BClFO₃
• 分子量: 244.458
• InChiKey: ADGCCVYMKHWYGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.62
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-(4-chloro-2-fluoro-3-methoxyphenyl)-1,3,2-dioxaborinane 在 bis-triphenylphosphine-palladium(II) chloride 、 potassium fluoride 、 水 、 potassium carbonate 、 sodium hydroxide 作用下， 以 甲醇 、 水 、 二甲基亚砜 、 乙腈 为溶剂， 反应 16.33h， 生成 氯氟吡啶酯
  参考文献：
  名称：

  The discovery of Arylex™ active and Rinskor™ active: Two novel auxin herbicides

  摘要：

  Multiple classes of commercially important auxin herbicides have been discovered since the 1940s including the aryloxyacetates (2,4-D, MCPA, dichlorprop, mecoprop, triclopyr, and fluroxypyr), the benzoates (dicamba), the quinoline-2-carboxylates (quinclorac and quinmerac), the pyrimidine-4-carboxylates (aminocyclopyrachlor), and the pyridine-2-carboxylates (picloram, clopyralid, and aminopyralid). In the last 10 years, two novel pyridine-2-carboxylate (or picolinate) herbicides were discovered at Dow AgroSciences. This paper will describe the structure activity relationship study that led to the discovery of the 6-aryl-picolinate herbicides Arylex (TM) active (2005) and Rinskor (TM) active (2010). While Arylex was developed primarily for use in cereal crops and Rinskor is still in development primarily for use in rice crops, both herbicides will also be utilized in additional crops. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2015.08.011
• 作为产物：
  描述：

  4-氯-2-氟-3-甲氧基苯硼酸 、 1,3-丙二醇 以 乙二醇二甲醚 、 正己烷 为溶剂， 生成 2-(4-chloro-2-fluoro-3-methoxyphenyl)-1,3,2-dioxaborinane
  参考文献：
  名称：

  PROCESS FOR THE SELECTIVE DEPROTONATION AND FUNCTIONALIZATION OF 1-FLUORO-2-SUBSTITUTED-3-CHLOROBENZENES

  摘要：

  1-氟-2-取代-3-氯苯可以选择性地去质子化，并在邻近氟取代基的位置进行官能化。

  公开号：

  US20090182168A1

文献信息

• [EN] PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF<br/>[FR] HERBICIDES CARBOXYLATES DE PYRIDINE ET DE PYRIMIDINE ET LEURS PROCÉDÉS D'UTILISATION
  申请人：DOW AGROSCIENCES LLC

  公开号：WO2019084353A1

  公开（公告）日：2019-05-02

  Provided herein are pyridine and pyrimidine carboxylates and their derivatives, and compositions and methods of use thereof as herbicides.

  本文提供吡啶和嘧啶羧酸盐及其衍生物，以及它们作为除草剂的组合物和使用方法。
• [EN] 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES<br/>[FR] 4-AMINOPICOLINATES ET LEUR UTILISATION EN TANT QU'HERBICIDES
  申请人：SYNGENTA LTD

  公开号：WO2010149956A1

  公开（公告）日：2010-12-29

  The present invention relates to substituted 4-aminopicolinates as well as N- oxides and agriculturally acceptable salts thereof, and their use in controlling plant growth, particularly undesirable plant growth, in crops of useful plants. The invention extends to herbicidal compositions comprising such compounds, N- oxides and/or salts as well as mixtures of the same with one or more further active ingredients and/or a safener.

  本发明涉及取代的4-氨基吡啶甲酸盐，以及它们的N-氧化物和农业上可接受的盐，以及它们在控制植物生长中的应用，特别是在有用植物作物中控制不需要的植物生长。本发明还包括含有此类化合物、N-氧化物和/或盐的除草组合物，以及与一个或多个其他活性成分和/或安全剂的混合物。
• 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides
  申请人：Balko W. Terry

  公开号：US20070179060A1

  公开（公告）日：2007-08-02

  4-Aminopicolinic acids having tri- and tetra-substituted aryl substituents in the 6-position, and their amine and acid derivatives, are potent herbicides demonstrating a broad spectrum of weed control.

  在6位具有三取代和四取代芳基取代基的4-氨基吡啶酸及其胺和酸衍生物是一类高效除草剂，展示出广泛的杂草控制谱。
• ARYLALKYL ESTERS OF 4-AMINO-6-(SUBSTITUTED PHENYL)-PICOLINATES AND 6-AMINO-2-(SUBSTITUTED PHENYL)-PYRIMIDINECARBOXYLATES AND THEIR USE AS SELECTIVE HERBICIDES FOR CROPS
  申请人：Yerkes Carla N.

  公开号：US20120190551A1

  公开（公告）日：2012-07-26

  Arylalkyl esters of 4-aminopicolinic acids and 6-amino-4-pyrimidinecarboxylates are herbicides for control of weeds especially those species common to rice and wheat cropping systems and in pasture management programs.

  芳基烷基对氨基吡啶甲酸酯和6-氨基-4-嘧啶羧酸酯是除草剂，用于控制杂草，特别是那些在稻田和小麦种植系统以及牧草管理计划中常见的物种。
• 3-ALKOXY, THIOALKYL AND AMINO-4-AMINO-6-(SUBSTITUTED)PICOLINATES AND THEIR USE AS HERBICIDES
  申请人：Epp Jeffrey B.

  公开号：US20130005574A1

  公开（公告）日：2013-01-03

  3-alkoxy, thioalkyl and amino-4-amino-6-(substituted)picolinic acids having a halogen, alkyl or mono-, di- tri- and tetra-substituted aryl substituents in the 6-position, and their acid derivatives, are herbicides demonstrating a broad spectrum of weed control.

  具有卤素、烷基或在6位具有单取代、双取代、三取代和四取代芳基取代基团的3-烷氧基、硫代烷基和氨基-4-氨基-6-(取代)吡啶甲酸及其酸衍生物是表现出广谱除草作用的除草剂。