7-tetradecyl-6,9-dioxa-2,13-dithia tetradecane

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 7-tetradecyl-6,9-dioxa-2,13-dithia tetradecane
• 英文别名: 1,2-Bis(3-methylsulfanylpropoxy)hexadecane；1,2-bis(3-methylsulfanylpropoxy)hexadecane
• 化学式: C₂₄H₅₀O₂S₂
• 分子量: 434.792
• InChiKey: AFJXTZBNEYQDAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  28
• 可旋转键数：
  24
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  69.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,2-十六烷二醇 、 3-(甲基硫代)丙基 4-甲基苯硫nate 在 sodium hydride 作用下， 生成 7-tetradecyl-6,9-dioxa-2,13-dithia tetradecane
  参考文献：
  名称：

  Silver Ion Selective Optodes Based on Novel Thia Ether Compounds

  摘要：

  Flow-through type fiber-optic silver ion selective optodes based on novel cyclic and noncyclic thia crown ether compounds and a Lipophilic anionic indicator dye have been developed. Pellicular octadecylsilica beads were coated with a lipophilic organic liquid containing the thia ether compound as the silver ion selective ionophore and LAD-3 as the color changeable indicator dye, The optode system was constructed by packing these color changeable ion sensing beads ina now-through optical cell (cell volume, 7 mu L) having a quartz window attached directly to the distal end of a bifurcated optical fiber. The optode based on a lipophilic thia crown ether that has two sulfur atoms (tetradecyl-14-dithiacrown-4) exhibited the most sensitive response to silver ion of all the optodes investigated. This optode could detect silver ion in concentrations ranging from 10(-6) to 10(-2) M at pH 7.0 with 0.05 M Tris-H2SO4 buffer as the flowing solution by measuring the absorbance change in the sensing beads at 516 mm. This optode showed a higher selective response to Ag+ without any interference from other transition metal ions, except for Hg2+, up to 10(-3) M, as well as alkali metal and alkaline earth metal ions up to 1 M. Optodes employing highly lipophilic ionophores showed good reproducible response to Ag+ for at least 2 weeks.

  DOI：

  10.1021/ac00104a003

文献信息

• Method for the preparation of optical (bio)chemical sensor devices
  申请人：——

  公开号：US20020115224A1

  公开（公告）日：2002-08-22

  The present invention relates to a method for the preparation of a miniaturized optical chemical or biochemical sensor device (e.g. bulk optode, etc. for ion sensing), said device comprising a substrate material having a planar surface portion, said planar surface representing a transducer based on an optical phenomenon such as surface plasmon resonance based on evanescent waves, reflection or transmission; said planar surface portion having arranged thereon an multi-analyte array of (bio)chemical sensor dots located at spatially separated predetermined positions of the planar surface, said sensor dots including (i) a polymer matrix, and (ii) one or more (bio)chemical recognition moieties, the method comprising (a) providing a substrate material having a planar surface portion; (b) providing one or more spotting fluid(s); (c) depositing the one or more spotting fluid(s) onto the planar surface portion of the substrate material by means of a pin-printer deposition mechanism (arrayer) and allowing the spotting fluid(s) to consolidate.

  本发明涉及一种制备微型光学化学或生化传感器装置（如用于离子传感的散装光电极等）的方法。本发明涉及一种用于制备微型化光学化学或生化传感器装置（如用于离子传感的体式光电二极管等）的方法，所述装置包括具有平面表面部分的基底材料，所述平面表面代表基于光学现象（如基于蒸发波、反射或透射的表面等离子体共振）的换能器；所述平面表面部分上排列有位于平面表面空间上分离的预定位置的（生物）化学传感点的多分析阵列，所述传感点包括 (i) 聚合物基质，和 (ii) 一个或多个（生物）化学识别分子，该方法包括 (a) 提供具有平面表面部分的基底材料；(b) 提供一种或多种点阵液； (c) 通过针刺机沉积机构（阵列器）将一种或多种点阵液沉积到基底材料的平面部分上，并使点阵液固化。
• METHOD FOR THE PREPARATION OF OPTICAL (BIO)CHEMICAL SENSOR DEVICES
  申请人：Vir A/S

  公开号：EP1360007A1

  公开（公告）日：2003-11-12
• [EN] METHOD FOR THE PREPARATION OF OPTICAL (BIO)CHEMICAL SENSOR DEVICES<br/>[FR] PROCEDE DE PREPARATION DE DISPOSITIFS DE DETECTION OPTIQUE (BIO)CHIMIQUES
  申请人：VIR AS

  公开号：WO2002066162A1

  公开（公告）日：2002-08-29

  The present invention relates to a method for the preparation of a miniaturized optical chemical or biochemical sensor device (e.g. bulk optode, etc. for ion sensing), said device comprising a substrate material having a planar surface portion, said planar surface representing a transducer based on an optical phenomenon such as surface plasmon resonance based on evanescent waves, reflection or transmission; said planar surface portions having arranged thereon an multi-analyte array of (bio)chemical sensor dots located at spatially separated predetermined positions of the planar surface, said sensor dots including (i) a polymer matrix, and (ii) on or more (bio)chemical recognition moieties, the method comprising (a) providing a substrate material having a planar surface portion; (b) providing one or more spotting fluid(s); (c) depositing the one or more spotting fluid(s) onto the planar surface portion of the substrate material by means of a pin-printer depositing mechanism (arrayer) and allowing the spotting fluid(s) to consolidate.
• Silver Ion Selective Optodes Based on Novel Thia Ether Compounds
  作者：Hideaki. Hisamoto、Eriko. Nakagawa、Kazuhisa. Nagatsuka、Yoko. Abe、Sayaka. Sato、Dwi. Siswanta、Koji. Suzuki

  DOI：10.1021/ac00104a003

  日期：1995.4.15

  Flow-through type fiber-optic silver ion selective optodes based on novel cyclic and noncyclic thia crown ether compounds and a Lipophilic anionic indicator dye have been developed. Pellicular octadecylsilica beads were coated with a lipophilic organic liquid containing the thia ether compound as the silver ion selective ionophore and LAD-3 as the color changeable indicator dye, The optode system was constructed by packing these color changeable ion sensing beads ina now-through optical cell (cell volume, 7 mu L) having a quartz window attached directly to the distal end of a bifurcated optical fiber. The optode based on a lipophilic thia crown ether that has two sulfur atoms (tetradecyl-14-dithiacrown-4) exhibited the most sensitive response to silver ion of all the optodes investigated. This optode could detect silver ion in concentrations ranging from 10(-6) to 10(-2) M at pH 7.0 with 0.05 M Tris-H2SO4 buffer as the flowing solution by measuring the absorbance change in the sensing beads at 516 mm. This optode showed a higher selective response to Ag+ without any interference from other transition metal ions, except for Hg2+, up to 10(-3) M, as well as alkali metal and alkaline earth metal ions up to 1 M. Optodes employing highly lipophilic ionophores showed good reproducible response to Ag+ for at least 2 weeks.