三甲基(2-吗啉-4-基乙氧基)硅烷 | 89841-36-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 中文名称: 三甲基(2-吗啉-4-基乙氧基)硅烷
• 英文名称: 4-<2-(Trimethylsiloxy)ethyl>morpholine
• 英文别名: 2-morpholinoethyl trimethylsilyl ether；Morpholine, 4-[2-[(trimethylsilyl)oxy]ethyl]-；trimethyl(2-morpholin-4-ylethoxy)silane
• CAS: 89841-36-1
• 化学式: C₉H₂₁NO₂Si
• 分子量: 203.357
• InChiKey: CFTVGFPIGRNPFO-UHFFFAOYSA-N

物化性质

• 沸点：
  226.2±25.0 °C(Predicted)
• 密度：
  0.933±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.17
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  三甲基(2-吗啉-4-基乙氧基)硅烷 在 氢氟酸 作用下， 反应 10.23h， 以33.5%的产率得到Perfluoro(morpholinoacetyl) fluoride
  参考文献：
  名称：

  Electrochemical fluorination of (N,N-dialkylamino)alcohols

  摘要：

  Series of amino alcohols including 2-(N,N-dialkylamino)ethanols, 3-(N,N-dimethylamino)propanol and 4-(N,N-dimethylamino)butanol were subjected to electrochemical fluorination. In the case of 2-(N,N-dialkylamino)ethanols, the F-(2-N, N-dialkylamino) acetyl fluorides were obtained in fair to good yields. Yields of each target compound were strongly dependent on the kind of the dialkylamino group. Cyclic amines having an N-(2-hydroxylethyl) group afforded the corresponding F-[N-(c-alkylamino)-substituted acetyl fluorides]. Their yields were generally better than those of acyclic analogs. Several 2-(N,N-dialkylamino)ethanols and 3-(N,N-dimethylamino)propanol were converted into the corresponding trimethylsilylethers, aminoalkyl methyl carbonates and bis-aminoalkyl carbonate, respectively, and they were subjected to fluorination for a comparison of the yield with that obtained from that of the parent aminoalcohol. (C) 1999 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-1139(99)00053-6
• 作为产物：
  描述：

  2-吗啉乙醇 、 三甲基氯硅烷 在 sodium methylate 作用下， 以 苯 为溶剂， 以65%的产率得到三甲基(2-吗啉-4-基乙氧基)硅烷
  参考文献：
  名称：

  Kumar, A.; Gurtu, S.; Sinha, J. N., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1983, vol. 22, # 10, p. 1072 - 1073

  摘要：

  DOI：

文献信息

• KUMAR, A.;GURTU, S.;SINHA, J. N.;BHARGAVA, K. P.;SHANKER, K., INDIAN J. CHEM., 1983, 22, N 10, 1072-1073
  作者：KUMAR, A.、GURTU, S.、SINHA, J. N.、BHARGAVA, K. P.、SHANKER, K.

  DOI：——

  日期：——