(Z)-1-benzylidene-2-phenylcyclopropane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (Z)-1-benzylidene-2-phenylcyclopropane
• 英文别名: (2-benzylidenecyclopropyl)benzene；[(2Z)-2-benzylidenecyclopropyl]benzene
• 化学式: C₁₆H₁₄
• 分子量: 206.287
• InChiKey: ATUIQBCKOCHOGP-PTNGSMBKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  苯乙烯 、 (2,2-二氯乙烯基)苯 在 [^i-PrNDI]Ni₂(C₆H₆) 、 锌 作用下， 以 乙醚 、 N,N-二甲基乙酰胺 为溶剂， 反应 24.0h， 以50%的产率得到
  参考文献：
  名称：

  催化还原性亚乙烯基转移反应

  摘要：

  亚甲基环丙烷是重要的合成中间体，其具有的应变能超过饱和环丙烷的应变能> 10 kcal / mol。该报告描述了利用1,1-二氯烯烃作为亚乙烯基前体的简单烯烃的催化还原性亚甲基环丙烷化反应。通过双核Ni催化剂促进反应，提出该双核Ni催化剂通过CC -Cl氧化加成而接近Ni 2（乙烯基类烯基）中间体。

  DOI：

  10.1021/jacs.7b05901

文献信息

• Divergent Oxidative Rearrangements in Solution and in a Zeolite:  Distal vs Proximal Bond Cleavage of Methylenecyclopropanes
  作者：Hiroshi Ikeda、Tsuyoshi Nomura、Kimio Akiyama、Mitsuhiro Oshima、Heinz D. Roth、Shozo Tero-Kubota、Tsutomu Miyashi

  DOI：10.1021/ja045930n

  日期：2005.10.1

  2-dihydronaphthalene (9) were isolated from the supernatant solution. The sharp contrast between the photoinduced electron-transfer reaction with photosensitizers in solution and the spontaneous reaction with redox-active acidic zeolite offers the prospect of further zeolite-induced regiodivergent reactions in a range of additional substrates.

  在 CH(2)Cl(2) 中存在 E-1-benzylidene-2-phenylcyclopropane (E-5) 的情况下照射 9,10-二氰基蒽 (DCA) 或对氯苯醌会导致 E-5 发生亚甲基环丙烷重排。DCA 和 5 之间的加合物 Z-7 坚定地支持双功能三亚甲基甲烷自由基阳离子的参与。相比之下，将 E-5 掺入 HZSM-5 会产生反式，反式-1,4-二苯基-1,3-丁二烯自由基阳离子，螯合在 HZSM-5 内部，tt-8(.+)@HZSM-5，通过 ESR 和漫反射光谱识别。此外，从上清液中分离出低产率的 tt-8、其顺式、反式异构体 (ct-8) 和 1-苯基-1,2-二氢萘 (9)。
• Reactions of the Lithium Salts of the Tribenzylidenemethane Dianion, Diphenylacetone Dianion, and Related Compounds
  作者：Ortrun Witt、Harald Mauser、Thomas Friedl、Dieter Wilhelm、Timothy Clark

  DOI：10.1021/jo971113c

  日期：1998.2.1

  Potentially synthetically useful reactions of the dilithium salts of the title dianions have been investigated, Electrophilic quenching with a variety of reagents usually leads to the expected products in good yield. Quenching the diphenylacetone dianion with 1 equiv of trimethylchlorosilane, however, gives a good yield of 1,3-diphenylallene obtained by formal elimination of a trimethylsiloxy anion from an intermediate monoquenched monoanion salt. NMR studies, however, do not reveal the intermediacy of the 1,3-diphenyl-2-(trimethylsiloxy)allyl anion but rather suggest that the initial reaction site is at carbon, rather than oxygen, Oxidation of the dianions leads either to ring closure or dimerization for the tribenzylidenemethane dianion and to dimerization for the diphenylacetone dianion. The dimerization reactions are stereospecific, both with respect to the two new stereocenters produced and for the double bonds of the bis-silyl enol ether products if the dimeric bis-enolate dianion products are quenched with trimethylchlorosilane.
• Catalytic Reductive Vinylidene Transfer Reactions
  作者：Sudipta Pal、You-Yun Zhou、Christopher Uyeda

  DOI：10.1021/jacs.7b05901

  日期：2017.8.30

  synthetic intermediates that possess strain energies exceeding those of saturated cyclopropanes by >10 kcal/mol. This report describes a catalytic reductive methylenecyclopropanation reaction of simple olefins, utilizing 1,1-dichloroalkenes as vinylidene precursors. The reaction is promoted by a dinuclear Ni catalyst, which is proposed to access Ni2(vinylidenoid) intermediates via C—Cl oxidative addition.

  亚甲基环丙烷是重要的合成中间体，其具有的应变能超过饱和环丙烷的应变能> 10 kcal / mol。该报告描述了利用1,1-二氯烯烃作为亚乙烯基前体的简单烯烃的催化还原性亚甲基环丙烷化反应。通过双核Ni催化剂促进反应，提出该双核Ni催化剂通过CC -Cl氧化加成而接近Ni 2（乙烯基类烯基）中间体。