三甲基(苯基硒代甲基)硅烷 | 56253-60-2

• 物质功能分类: 化学试剂 - 硅烷试剂
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 三甲基(苯基硒代甲基)硅烷
• 中文别名: (苯基锡甲基)三甲基硅烷
• 英文名称: trimethyl-phenylselanylmethyl-silane
• 英文别名: Phenylselenotrimethylsilylmethane；phenylselenomethyltrimethylsilane；Trimethyl[(phenylseleno)methyl]silane；(phenylselenomethyl)trimethylsilane；Phenylselenomethyltrimethylsilan；Trimethyl((phenylseleno)methyl)silane；trimethyl(phenylselanylmethyl)silane
• CAS: 56253-60-2
• 化学式: C₁₀H₁₆SeSi
• mdl: MFCD00042834
• 分子量: 243.283
• InChiKey: QXFASNHOOXGHDD-UHFFFAOYSA-N

物化性质

• 沸点：
  106 °C6 mm Hg(lit.)
• 密度：
  1.176 g/mL at 25 °C(lit.)
• 闪点：
  >230 °F
• 稳定性/保质期：
  遵照规定使用和储存，则不会发生分解。

计算性质

• 辛醇/水分配系数(LogP)：
  4.06
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• TSCA：
  No
• 危险等级：
  6.1(b)
• 危险品标志：
  T,N
• 安全说明：
  S20/21,S28,S45,S60,S61
• 危险类别码：
  R50/53,R23/25,R33
• WGK Germany：
  3
• 危险品运输编号：
  UN 2810 6.1/PG 3
• 包装等级：
  III
• 危险类别：
  6.1(b)

SDS

Version 1.2
Regulation (EC) No 1907/2006

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1 - Product and Company Information

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Product Name (PHENYLSELENOMETHYL)TRIMETHYLSILANE, 99%

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2 - Hazards Identification

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SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Toxic by inhalation and if swallowed. Danger of cumulative
effects. Very toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment.

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3 - Composition/Information on Ingredients

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Product Name CAS # EC no Annex I
Index Number
(PHENYLSELENOMETHYL)TRIMETHYLSILAN 56253-60-2 260-077-3 034-002-00-8
E
Formula C10H16SeSi
Molecular Weight 243,2900 AMU

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4 - First Aid Measures

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AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.

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5 - Fire Fighting Measures
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EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

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6 - Accidental Release Measures

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PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Cover with dry lime or soda ash, pick up, keep in a closed
container, and hold for waste disposal. Ventilate area and wash
spill site after material pickup is complete.

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7 - Handling and Storage

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HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing.
STORAGE
Conditions of Storage: Keep tightly closed. Store in a cool dry
place.

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8 - Exposure Controls / Personal Protection

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ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling. Wash contaminated clothing before
reuse.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US)
or CEN (EU). Where risk assessment shows air-purifying respirators
are appropriate use a full-face respirator with multi-purpose
combination (US) or type ABEK (EN 14387) respirator cartridges as
a backup to engineering controls. If the respirator is the sole
means of protection, use a full-face supplied air respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.

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9 - Physical and Chemical Properties

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Appearance Color: Deep yellow-green
Form: Clear liquid
Property Value At Temperature or Pressure
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pH N/A
BP/BP Range 106,000 °C 6,000 mmHg
MP/MP Range N/A
Flash Point 95,000 °C Method: closed cup
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density 1,1760 g/cm3
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A

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10 - Stability and Reactivity

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STABILITY
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Silicon oxide, Selenium/selenium oxides.

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11 - Toxicological Information

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SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Multiple Routes: May be harmful by inhalation, ingestion, or
skin absorption. May cause irritation.
TARGET ORGAN INFORMATION
Liver.

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12 - Ecological Information

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No data available.

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13 - Disposal Considerations

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SUBSTANCE DISPOSAL
Dissolve or mix the material with a combustible solvent and burn
in a chemical incinerator equipped with an afterburner and
scrubber. Observe all federal, state, and local environmental
regulations.

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14 - Transport Information
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RID/ADR
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
IMDG
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 2810
Class: 6.1
PG: III
Proper Shipping Name: Toxic liquid, organic, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required

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15 - Regulatory Information

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CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 034-002-00-8
NOTA: A
INDICATION OF DANGER: T-N
Toxic. Dangerous for the environment.
R-PHRASES: 23/25-33-50/53
Toxic by inhalation and if swallowed. Danger of cumulative
effects. Very toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment.
S-PHRASES: 20/21-28-45-60-61
When using do not eat, drink, or smoke. After contact with
skin, wash immediately with plenty of soap-suds. In case of
accident or if you feel unwell, seek medical advice immediately
(show the label where possible). This material and its
container must be disposed of as hazardous waste. Avoid release
to the environment. Refer to special instructions/safety data
sheets.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
Self-Classification

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16 - Other Information

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WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Inc.,
shall not be held liable for any damage resulting from handling or
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from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2010 Co. License granted to make
unlimitedpaper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  三甲基(苯基硒代甲基)硅烷 在 氨 、 sodium 作用下， 以 叔丁醇 为溶剂， 生成 二苯基二硒醚
  参考文献：
  名称：

  苯基硒烷的苯基硒键的光还原裂解

  摘要：

  从三乙胺到苯硒代链烷烃的光诱导电子转移可导致PhSe键的选择性还原和裂解，从而导致苯和相应的二烯化烯基硒基自由基的形成。

  DOI：

  10.1016/0040-4039(94)88021-2
• 作为产物：
  描述：

  2,2,3,3,4,4,4-Heptafluoro-1-phenylselanylbutan-1-ol 、 氯甲基三甲基硅烷 在 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 四氢呋喃 为溶剂， 反应 0.5h， 以54%的产率得到三甲基(苯基硒代甲基)硅烷
  参考文献：
  名称：

  1-(Organoselanyl)perfluoroalkanols: A Stable and Efficient Precursor for Organoselenols

  摘要：

  成功制备了 1-(有机硒基)全氟烷醇 1、3、4 和 10，并与己酰氯反应生成了相应的酯 5、7 和 8 以及硒酯 6。在 DBU 介导下，七氟丁醇 4、10 和 α-对硝基苯甲酸酯 2 与烷基卤化物发生烷基化反应，很容易就能得到烷基苯基硒化物 9a-9i 和 11a-11c，收率从好到高。

  DOI：

  10.1246/cl.2008.1046

文献信息

• gem-Heterosubstituted (stannyl)methylsilanes as synthetic equivalents of functionalized α-stannyl(methyl) anions
  作者：Damiano Tanini、Tiziano Nocentini、Antonella Capperucci

  DOI：10.24820/ark.5550190.p011.038

  日期：——

  Received mm-dd-yyyy Accepted mm-dd-yyyy Published on line mm-dd-yyyy Dates to be inserted by editorial office Abstract α-Heterosubstituted silyl derivatives, such as phenylthio-, phenylselenoand benzotriazolyl-stannyl silanes, react with aldehydes under TBAF catalysis, leading to α-substituted-β-hydroxy stannanes, able to behave as precursors of Zand E-olefins, generated by deoxystannylation. This

  收到 mm-dd-yyyy 接受 mm-dd-yyyy 在线发布 mm-dd-yyyy 编辑部插入的日期 摘要 α-杂取代的甲硅烷基衍生物，如苯硫基、苯基硒基和苯并三唑基-甲锡基硅烷，在 TBAF 下与醛反应催化，导致 α-取代-β-羟基锡烷，能够充当 Zand E-烯烃的前体，由脱氧锡烷基化产生。这种反应性表明这种杂取代的硅烷能够通过碳-硅键的温和官能化充当掩蔽的碳负离子。
• The reactions of lithiobisphenylselenomethane with chloromethyltrimethylsilane and iodomethyltrimethylstannane: Novel 1,1 - and 1,2- elimination reactions in organoselenium/organotin chemistry
  作者：Tarun K. Sarkar、Tushar K. Satapathi

  DOI：10.1016/s0040-4039(00)99236-0

  日期：1989.1

  Anomalous and unprecedented 1,1- and 1,2-elimination reactions are reported in the alkylation of lithiobisphenylselenomethane 4 with chloromethyltrimethylsilane and iodomethyltrimethylstannane.

  据报道，在硫代双苯基硒代甲烷4与氯甲基三甲基硅烷和碘甲基三甲基锡烷的烷基化反应中，发生了异常且前所未有的1,1和1,2-消除反应。
• (2,3)-1,2-epoxy-3-butanol. A useful synthon for the preparation of chiral 1,2-diols.
  作者：James D. White、Myung-chol Kang、Bernard G. Sheldon

  DOI：10.1016/s0040-4039(00)85949-3

  日期：1983.1
• Transformation of α-phenylseleneketones to allylic selenides via migration of the phenylseleno group
  作者：Hisao Nishiyama、Kazuyoshi Itagaki、Noriyuki Osaka、Kenji Itoh

  DOI：10.1016/s0040-4039(00)88359-8

  日期：1982.1
• Chadha, Raj K.; Chehayber, Jaafar M.; Drake, John E., Inorganic Chemistry, 1986, vol. 25, # 5, p. 611 - 615
  作者：Chadha, Raj K.、Chehayber, Jaafar M.、Drake, John E.

  DOI：——

  日期：——

表征谱图