1,4-bis(3',4'-dimethoxyphenyl)-4-methoxybutan-1-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,4-bis(3',4'-dimethoxyphenyl)-4-methoxybutan-1-one
• 英文别名: 1,4-Bis(3,4-dimethoxyphenyl)-4-methoxybutan-1-one
• 化学式: C₂₁H₂₆O₆
• 分子量: 374.434
• InChiKey: BBIGVGTWWRLDPV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  27
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  63.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  甲醇 、 3,4-二甲氧基苯乙烯 在 ammonium cerium(IV) nitrate 作用下， 反应 0.5h， 以74%的产率得到1,4-bis(3',4'-dimethoxyphenyl)-1,4-dimethoxybutane
  参考文献：
  名称：

  Novel Cerium(IV) ammonium nitrate induced dimerization of methoxystyrenes

  摘要：

  Methoxystyrenes undergo facile dimerization when heated with Cerium (IV) ammonium nitrate in methanol; cyclized products are obtained in acetonitrile. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)00279-7

文献信息

• Cerium(IV) Ammonium Nitrate Induced Dimerization of Methoxystyrenes
  作者：Vijay Nair、V. Sheeba、Sreeletha B. Panicker、Tesmol G. George、Roshini Rajan、Lakshmi Balagopal、M. Vairamani、S. Prabhakar

  DOI：10.1016/s0040-4020(00)00054-5

  日期：2000.4

  4-Methoxystyrene 1 underwent dimerization to 1,4-diphenylbutane derivatives 5 and 6 in presence of CAN in methanol. But in ethanol the same reaction afforded a tetralone derivative along with 5 and 6. 3,4-Dimethoxystyrene 10 underwent dimerization in presence of CAN in methanol to afford acyclic as well as cyclic products. 3,4,5-Trimethoxystyrene 12 in presence of CAN in methanol afforded only the cyclized dimers, the tetralone 21 and the tetralin derivative 22. (C) 2000 Elsevier Science Ltd. All rights reserved.