4-(naphthalen-1-yl)-2-phenyl-1H-imidazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4-(naphthalen-1-yl)-2-phenyl-1H-imidazole
• 英文别名: 2-phenyl-4-(1-naphthyl)imidazole；2-Phenyl-4-(1-naphthyl) imidazole；5-naphthalen-1-yl-2-phenyl-1H-imidazole
• 化学式: C₁₉H₁₄N₂
• 分子量: 270.334
• InChiKey: JQJKWVIUFZWDPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  28.7
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  苯甲脒 、 2-溴-1-萘-1-乙酮 以 四氢呋喃 为溶剂， 反应 1.0h， 以33.3%的产率得到4-(naphthalen-1-yl)-2-phenyl-1H-imidazole
  参考文献：
  名称：

  [EN] PHENYLNAPHTHYLIMIDAZOLES FOR USE ON COPPER SURFACES DURING SOLDERING
  [FR] PHÉNYLNAPHTHYLIMIDAZOLES EN VUE D'UNE UTILISATION SUR LES SURFACES EN CUIVRE AU COURS D'UN BRASAGE

  摘要：

  含有所述下列公式表示的新型苯基萘基咪唑啉化合物的表面处理剂与铜或铜合金的表面接触。在公式中，当A1是苯基时，A2代表1-萘基或2-萘基，当A1是1-萘基或2-萘基时，A2代表苯基；R代表氢原子或甲基。

  公开号：

  WO2005121101A1

文献信息

• Imidazoles from nitroallylic acetates and α-bromonitroalkenes with amidines: synthesis and trypanocidal activity studies
  作者：Elumalai Gopi、Tarun Kumar、Rubem F. S. Menna-Barreto、Wagner O. Valença、Eufrânio N. da Silva Júnior、Irishi N. N. Namboothiri

  DOI：10.1039/c5ob01444a

  日期：——

  Cascade reactions of amidines with nitroallylic acetates and α-bromonitroalkenes provide potentially bioactive imidazoles in good to excellent yields in most cases. While 2,4-disubstituted imidazol-5-yl acetates are formed in the first case, 2,4-disubstituted imidazoles, bearing no substituent at position 5, are the products in the second case. These two series of imidazoles, viz. 2,4,5-trisubstituted

  在大多数情况下，am与乙酸烯丙酯和α-溴硝基烯烃的级联反应可提供潜在的具有生物活性的咪唑，其收率良好至极佳。在第一种情况下形成2,4-二取代的咪唑-5-基乙酸盐，而在第二种情况下形成2,4-二取代的咪唑，它们在5位不带取代基。这两个咪唑系列，即。筛选了2,4,5-三取代和2,4-二取代的抗原生动物寄生虫克氏锥虫的活性，锥虫是南美锥虫病的病因。多达三种化合物的活性与标准苯并咪唑一样，而另外两种化合物的活性则高2–3倍，这突出了取代的咪唑的潜力，它很容易从硝基烯烃中获得，并可能是抗寄生虫药。
• Phenylnaphthylimidazole Compound and Usage of the Same
  申请人：Hirao Hirohiko

  公开号：US20070246134A1

  公开（公告）日：2007-10-25

  A surface treating agent containing a novel phenylnaphthylimidazole compound represented by the following formula is brought into contact with the surface of copper or a copper alloy. In the formula, when A 1 is a phenyl group, then A 2 represents a 1-naphthyl group or a 2-naphthyl group, and when A 1 is a 1-naphthyl group or a 2-naphthyl group, then A 2 represents a phenyl group; and R represents a hydrogen atom or a methyl group.

  一种表面处理剂，其含有一种新的苯基萘亚咪唑化合物，其化学式如下，与铜或铜合金的表面接触。在该式中，当A1为苯基时，A2表示1-萘基或2-萘基，当A1为1-萘基或2-萘基时，A2表示苯基；R表示氢原子或甲基基团。
• PHENYLNAPHTHYLIMIDAZOLE COMPOUND AND USAGE OF THE SAME
  申请人：Hirao Hirohiko

  公开号：US20120199385A1

  公开（公告）日：2012-08-09

  A surface treating agent containing a novel phenylnaphthylimidazole compound represented by the following formula is brought into contact with the surface of copper or a copper alloy. In the formula, when A 1 is a phenyl group, then A 2 represents a 1-naphthyl group or a 2-naphthyl group, and when A 1 is a 1-naphthyl group or a 2-naphthyl group, then A 2 represents a phenyl group; and R represents a hydrogen atom or a methyl group.

  一种表面处理剂，包含以下公式所表示的新型苯基萘亚咪唑化合物，与铜或铜合金的表面接触。在公式中，当A1为苯基时，A2代表1-萘基或2-萘基，当A1为1-萘基或2-萘基时，A2代表苯基；而R代表氢原子或甲基基团。
• Phenylnaphthylimidazole compound and usage of the same
  申请人：Hirao Hirohiko

  公开号：US08378116B2

  公开（公告）日：2013-02-19

  A surface treating agent containing a novel phenylnaphthylimidazole compound represented by the following formula is brought into contact with the surface of copper or a copper alloy. In the formula, when A1 is a phenyl group, then A2 represents a 1-naphthyl group or a 2-naphthyl group, and when A1 is a 1-naphthyl group or a 2-naphthyl group, then A2 represents a phenyl group; and R represents a hydrogen atom or a methyl group.

  一种含有新型苯基萘亚咪唑化合物的表面处理剂与铜或铜合金的表面接触。在公式中，当A1为苯基时，A2代表1-萘基或2-萘基，当A1为1-萘基或2-萘基时，A2代表苯基；R代表氢原子或甲基基团。
• PHENYLNAPHTHYLIMIDAZOLES FOR USE ON COPPER SURFACES DURING SOLDERING
  申请人：SHIKOKU CHEMICALS CORPORATION

  公开号：EP1753728A1

  公开（公告）日：2007-02-21