N-hydroxy-N-methylglucamine

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-hydroxy-N-methylglucamine
• 英文别名: (2R,3R,4R,5S)-6-[hydroxy(methyl)amino]hexane-1,2,3,4,5-pentol
• 化学式: C₇H₁₇NO₆
• 分子量: 211.215
• InChiKey: IJOKKPRQJHRBJF-BDVNFPICSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.9
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  125
• 氢给体数：
  6
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  N-甲基-D-葡胺 在 双氧水 作用下， 以 de-ionized water 为溶剂， 反应 2.75h， 生成 N-hydroxy-N-methylglucamine
  参考文献：
  名称：

  Free radical inhibitors for quenching aqueous phase polymer growth and related methods

  摘要：

  公开了用于抑制自由基聚合的水相抑制剂，包括具有亲水尾部的自由基抑制剂，以及涂层和相关方法。在一种实施例中，自由基抑制剂可以是N-羟胺或N-亚硝胺，亲水尾部可以是多元醇尾部，抑制剂可以是浓缩液介质中的浓缩物，例如水、酒精和二者的混合物。

  公开号：

  US06348629B1

文献信息

• Hemocompatible polymer systems & related methods
  申请人：——

  公开号：US20040076845A1

  公开（公告）日：2004-04-22

  A polymer system with a hemocompatible film or coating is provided, the system comprises an organic phase and an aqueous phase, the organic phase comprises polymerizable monomers and at least one initiator and the aqueous phase comprises at least one dispersing agent, at least one free radical inhibitor and at least one buffering agent, the organic phase is immiscible in the aqueous phase, and the dispersing agent forms a hemocompatible surface on the polymer.

  提供了一种具有血液相容性薄膜或涂层的聚合物体系，该体系包括有机相和水相，有机相包括可聚合单体和至少一种引发剂，水相包括至少一种分散剂、至少一种自由基抑制剂和至少一种缓冲剂，有机相不溶于水相，分散剂在聚合物上形成血液相容性表面。
• Hemocompatible polymer systems and related devices
  申请人：Albright L. Robert

  公开号：US20070160848A1

  公开（公告）日：2007-07-12

  A polymer system and device with a hemocompatible film or coated polymers is provided, the polymer system comprises an organic phase and an aqueous phase, the organic phase comprises polymerizable monomers and at least one initiator and the aqueous phase comprises at least one dispersing agent, at least one free radical inhibitor and at least one buffering agent, the organic phase is immiscible in the aqueous phase, and the dispersing agent forms a hemocompatible surface on the polymer, and the device comprises a housing for containing the polymer system.
• Size-selective hemocompatible polymer system
  申请人：Young Wei-Tai

  公开号：US20120238441A1

  公开（公告）日：2012-09-20

  A size-selective hemocompatible porous polymeric adsorbent system is provided, the polymer system comprises at least one crosslinking agent and at least one dispersing agent, and the polymer has a plurality of pores with diameters in the range from about 17 to about 40,000 Angstroms
• SIZE-SELECTIVE HEMOCOMPATIBLE POLYMER SYSTEM
  申请人：Cytosorbents, Inc.

  公开号：US20180280602A1

  公开（公告）日：2018-10-04

  A size-selective hemocompatible porous polymeric adsorbent system is provided, the polymer system comprises at least one crosslinking agent and at least one dispersing agent, and the polymer has a plurality of pores with diameters in the range from about 17 to about 40,000 Angstroms.
• US5028625A
  申请人：——

  公开号：US5028625A

  公开（公告）日：1991-07-02