1-decyl α-D-lyxopyranoside

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-decyl α-D-lyxopyranoside
• 英文别名: decyl-α-D-lyxopyranoside；(2S,3S,4S,5R)-2-decoxyoxane-3,4,5-triol
• 化学式: C₁₅H₃₀O₅
• 分子量: 290.4
• InChiKey: MQBINCZBFIJILB-QPSCCSFWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  20
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  79.2
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  D-lyxose 、 癸醇 在 SiO₂ supported phosphomolybdic acid 作用下， 反应 0.08h， 以62%的产率得到1-decyl α-D-lyxopyranoside
  参考文献：
  名称：

  生物来源的表面活性剂：Mo（VI）和微波在木聚糖基非离子表面活性剂合成中的作用。

  摘要：

  微波辅助的磷钼酸（PMoA）催化的，未经保护的d-木糖和d-木糖的串联糖基化反应，是在Mo（VI）催化的木聚糖水解-表观电子化反应后获得的，可在较短的反应时间内提供烷基木糖苷和lyxosides。以非常好的收率（38-73％）制备了一系列在链结构上不同的两亲烷基戊糖苷的同源序列（C8-C14）。使用可重复使用的非均相PMoA / SiO2催化剂的新催化方法在产量，环境安全性，操作简便性方面均具有优势，从而为合理利用半纤维素生物质开辟了新视野。

  DOI：

  10.1016/j.carbpol.2016.02.070

文献信息

• ANTI-DANDRUFF SUGARS
  申请人：L'OREAL

  公开号：US20150250698A1

  公开（公告）日：2015-09-10

  The invention relates to the cosmetic use of at least one compounds according to the following formula (I), as an anti-dandruff agent or for preventing and/or treating scalp dandruff: where “sugar” denotes a monosaccharide residue chosen from rhamnose, xylose, fucose, mannose, lyxose, and arabinose; where R, substituting the anomeric oxygen in the sugar (represented by “O” in formula (I)), denotes a radical comprising 6 to 38 carbon atoms chosen from: —a linear or branched, saturated alkyl radical; —a linear or branched, alkenyl radical; said linear or branched saturated alkyl radical being optionally substituted by at least one OH and/or NH2 function; —if “sugar” denotes a mannose residue, R denotes a linear C6-C38 alkyl radical, substituted by at least one OH function or an NH2 function; and the salts and solvates and/or optical isomers thereof, alone or in a mixture, particularly racemic forms. The invention also relates to compounds according to formula (I), and cosmetic compositions containing same.

  本发明涉及至少一种根据以下公式（I）的化合物的化妆品用途，作为抗屑剂或用于预防/治疗头皮屑：其中“糖”表示一个单糖残基，选自鼠李糖、木糖、岩藻糖、甘露糖、来苏糖和阿拉伯糖；其中R代表糖（由公式（I）中的“O”表示）的异构氧上的一个基团，该基团包含6至38个碳原子，选自以下几种：—线性或支链的饱和烷基；—线性或支链的烯丙基；所述的线性或支链的饱和烷基可选择性地被至少一个OH和/或NH2功能基团取代；—如果“糖”表示一个甘露糖残基，R表示一个线性的C6-C38烷基，被至少一个OH功能或NH2功能取代；以及所述化合物的盐、溶剂化物和/或光学异构体，单独或混合使用，尤其是外消旋形式。本发明还涉及根据公式（I）的化合物，以及含有该化合物的化妆品组合物。
• US9833397B2
  申请人：——

  公开号：US9833397B2

  公开（公告）日：2017-12-05
• [EN] ANTI-DANDRUFF SUGARS<br/>[FR] SUCRES ANTIPELLICULAIRES
  申请人：OREAL

  公开号：WO2014044779A2

  公开（公告）日：2014-03-27

  The invention relates to the cosmetic use of at least one compounds according to the following formula (I), as an anti-dandruff agent or for preventing and/or treating scalp dandruff: where "sugar" denotes a monosaccharide residue chosen from rhamnose, xylose, fucose, mannose, lyxose, and arabinose; where R, substituting the anomeric oxygen in the sugar (represented by "O" in formula (I)), denotes a radical comprising 6 to 38 carbon atoms chosen from: - a linear or branched, saturated alkyl radical; - a linear or branched, alkenyl radical; said linear or branched saturated alkyl radical being optionally substituted by at least one OH and/or NH2 function; - if "sugar" denotes a mannose residue, R denotes a linear C6-C38 alkyl radical, substituted by at least one OH function or an NH2 function; and the salts and solvates and/or optical isomers thereof, alone or in a mixture, particularly racemic forms. The invention also relates to compounds according to formula (I), and cosmetic compositions containing same.
• Surfactants of biological origin: The role of Mo(VI) and microwaves in the synthesis of xylan-based non-ionic surfactants
  作者：Zuzana Hricovíniová

  DOI：10.1016/j.carbpol.2016.02.070

  日期：2016.6

  glycosylation of unprotected d-xylose and d-lyxose, obtained after tandem Mo(VI)-catalyzed xylan hydrolysis-epimerization reaction, provides alkyl xylosides and lyxosides in short reaction times. A homologous series of amphiphilic alkyl pentosides varying in chain structure (C8-C14) was prepared in very good yields (38-73%). A new catalytic approach using the reusable heterogeneous PMoA/SiO2 catalyst provides

  微波辅助的磷钼酸（PMoA）催化的，未经保护的d-木糖和d-木糖的串联糖基化反应，是在Mo（VI）催化的木聚糖水解-表观电子化反应后获得的，可在较短的反应时间内提供烷基木糖苷和lyxosides。以非常好的收率（38-73％）制备了一系列在链结构上不同的两亲烷基戊糖苷的同源序列（C8-C14）。使用可重复使用的非均相PMoA / SiO2催化剂的新催化方法在产量，环境安全性，操作简便性方面均具有优势，从而为合理利用半纤维素生物质开辟了新视野。